A tale of two vaccines: Lessons from polio that could inform the development of an HIV vaccine

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A tale of two vaccines: Lessons from polio that could inform the development of an HIV vaccine
J Esparza – AIDS, 2012

Abstract Two vaccine trials that were conducted 50 years apart are reviewed and compared: The 1954 field trial of the Salk inactivated polio vaccine and the RV144 HIV vaccine trial conducted in Thailand between 2003 and 2009. Despite the obvious differences in…