Jun 29, 2013 Volume 381 Number 9885 p2223 – 2298
Ukraine at risk of polio outbreak
A combination of public mistrust in vaccinations, poor vaccine supply, and corruption in the health system has left Ukraine with worryingly low rates of immunisation. Ed Holt reports.
Standardised case definitions for adverse events following immunisation
Comparability of data obtained in different vaccine trials is of interest for those who want to assess reactogenicity and safety profiles of specific vaccines. In this regard, the Brighton Collaboration (founded in 2000) has set internationally recognised standards by creating case definitions for many adverse events following immunisation (AEFI), and by developing standards for the collection and reporting of safety data in clinical trials.1