Science Translational Medicine
24 July 2013 vol 5, issue 195
Preventing Newborn Infection with Maternal Immunization
Steven Black, Immaculada Margarit, and Rino Rappuoli
24 July 2013: 195ps11
Group B streptococcal disease is a common cause of bacterial sepsis in newborns and is often fatal. To protect these babies, a vaccination program must target pregnant women for immunization so that the resulting antibodies can be passively delivered from the mother to the fetus. Scientists met in Siena, Italy, to discuss potential approaches to maternal immunization for the prevention of perinatal group B streptococcal disease.