Association Between Pandemic Influenza A(H1N1) Vaccination in Pregnancy and Early Childhood Morbidity in Offspring

JAMA Pediatrics
March 1, 2017, Vol 171, No. 3, Pages 207-312
http://archpedi.jamanetwork.com/issue.aspx

Original Investigation
Association Between Pandemic Influenza A(H1N1) Vaccination in Pregnancy and Early Childhood Morbidity in Offspring
Anders Hviid, DrMedSci; Henrik Svanström, PhD; Ditte Mølgaard-Nielsen, MSc; et al.
JAMA Pediatr. 2017;171(3):239-248. doi:10.1001/jamapediatrics.2016.4023
This cohort study evaluates whether influenza A(H1N1) vaccination in pregnancy is associated with early childhood morbidity in offspring.
Key Points
Question  Is pandemic influenza A(H1N1) vaccination in pregnancy associated with an increased risk for early childhood morbidity in offspring?
Findings  In this cohort study, children exposed to maternal vaccination during pregnancy were not significantly more likely to be hospitalized in early childhood than unexposed children.
Meaning  These results support the safety profile of influenza A(H1N1) vaccine used in pregnancy.