07 April 2017 Vol 356, Issue 6333
Books et al. – Reproducibility
On rigor and replication
Leonard P. Freedman
Rigor Mortis: How Sloppy Science Creates Worthless Cures, Crushes Hopes, and Wastes Billions Richard Harris Basic Books, 2017. 288 pp.
In Rigor Mortis: How Sloppy Science Creates Worthless Cures, Crushes Hopes, and Wastes Billions, a sensationalistic title belies a carefully crafted book about data reproducibility and scientific rigor in biomedical research. Although the book breaks no new ground, at a time when the so-called “irreproducibility crisis” has stoked passionate debate among scientists, bewildered the public, and even launched new disciplines (e.g., metaresearch), an accessible overview of the problem is most welcome.