NIH [to 22 April 2017]
April 21, 2017
NIH Funds Seven International Centers of Excellence for Malaria Research
The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, today announced approximately $9 million in first-year funding, subject to availability, for seven malaria research centers around the world. The 7-year awards continue NIAID’s 2010 program that created the International Centers of Excellence for Malaria Research (ICEMRs) in regions where malaria is endemic. The awards fund three new and four existing centers that work in 14 countries in Africa, Asia and Latin America.
The recipients of the ICEMR awards announced today are as follows:
:: Amazonian Center of Excellence in Malaria Research
Principal Investigator: Joseph Vinetz, M.D.
Lead Institution: University of California, San Diego
:: Multidisciplinary Research for Malaria Control and Prevention in West Africa*
Principal Investigator: Seydou Doumbia, M.D., Ph. D.
Lead Institution: University of Sciences, Techniques & Technologies of Bamako, Bamako, Mali
:: Malaria Transmission and the Impact of Control Efforts in Southern and Central Africa
Principal Investigator: William Moss, M.D.
Lead Institution: Johns Hopkins Bloomberg School of Public Health, Baltimore
:: Program for Resistance, Immunology, Surveillance & Modeling of Malaria in Uganda (PRISM)
Principal Investigator: Grant Dorsey, M.D.
:: Environmental Modifications in sub-Saharan Africa: Changing Epidemiology, Transmission and Pathogenesis of Plasmodium falciparum and P. vivax Malaria*
Principal Investigator: Guiyun Yan, Ph.D.
Lead Institution: University of California, Irvine
:: Southeast Asia Malaria Research Center
Principal Investigator: Liwang Cui, Ph.D.
Lead Institution: Pennsylvania State University, University Park
:: Myanmar Regional Center of Excellence for Malaria Research*
Principal Investigators: Christopher Plowe, M.D., M.P.H., and Myaing Myaing Nyunt, M.D., M.P.H., Ph.D.
Lead Institution: University of Maryland School of Medicine, Baltimore
IAVI – International AIDS Vaccine Initiative [to 22 April 2017]
IAVI REPORT – VOL. 21, NO. 1, 2017
This issue of IAVI Report marks an important milestone—it ushers the publication into its third decade.
Much has changed in HIV research during the last 20 years. Life-saving antiretroviral therapy works remarkably well, new prevention approaches such as pre-exposure prophylaxis have been proven highly effective, and vaccine research is progressing both clinically, with a recently launched efficacy trial, and pre-clinically, with several candidates being designed to elicit broadly neutralizing antibodies.
The style of IAVI Report has changed quite dramatically too. The content is broader, with coverage of more diverse vaccine-related issues and HIV prevention efforts at large. There are also many new features that were introduced over the years, among them the beautiful scientific images that grace the cover…
UNAIDS [to 22 April 2017]
Selected Press Releases & Updates
The living legacy of the Global Plan
20 April 2017
The Journal of Acquired Immune Deficiency Syndromes (JAIDS) has released a special supplement on the incredible journey of the Global plan towards the elimination of new HIV infections among children by 2015 and keeping their mothers alive (Global Plan), which documents the history of the Global Plan and outlines what the future holds as efforts to end AIDS among women, children and adolescents accelerate…
European Medicines Agency [to 22 April 2017]
Meeting highlights from the Committee for Medicinal Products for Human Use (CHMP) 18-21 April 2017
Eleven medicines recommended for approval, including four orphans
European Vaccine Initiative [to 22 April 2017]
18 April 2017
The meeting report from the EDUFLUVAC workshop on “Immunoassay standardisation for universal influenza vaccines” is now online.
Global Fund [to 22 April 2017]
Global Fund Names Rutger de Witt Wijnen Interim General Counsel
21 April 2017
The Global Fund to Fight AIDS, Tuberculosis and Malaria today announced that with effect from 1 June 2017, Rutger de Witt Wijnen will become Interim General Counsel at the Global Fund.
De Witt Wijnen, currently General Counsel at Green Climate Fund, has more than 30 years of experience as an attorney and has held varied private and public legal responsibilities in Europe, North America and Asia. He takes over the position of Gülen Newton, who left earlier this year.
Wellcome Trust [to 22 April 2017]
News / Published: 20 April 2017 Infectious disease and the immune system
New types of blood cells discovered
Scientists have identified new classes of cells in the human immune system.
The cells are new classes of types of white blood cells called dendritic cells and monocytes. Researchers have identified two new dendritic cell subtypes and two monocyte subtypes. They have also discovered a new dendritic cell progenitor.
Wellcome-funded researchers used a technique called single-cell genomics to analyse gene expression patterns in individual human blood cells. Previously, different types of immune cells were investigated and defined by the set of marker proteins that they express on their surface. This new technique is much more powerful and can reveal previously unrecognised and rare cell types that would be otherwise difficult to find.
Dendritic cells display molecules called antigens on their surfaces. These molecules are recognised by T cells which then mount an immune response. Monocytes are the largest type of white blood cell and can develop into macrophages that digest debris in our cells.
Divya Shah, from Wellcome’s Infection and Immunobiology team, says: “Two important white blood cell types in our bodies help defend us from infection – dendritic cells and monocytes. In this study, scientists have used cutting-edge technologies to find that there are many more types of cell than we originally thought. The next step is to find out what each of these cell types do in our immune system, both when we’re healthy and during disease.”…