Lancet Infectious Diseases May 2017 Volume 17 Number 5 p461-562 e128-e165

Lancet Infectious Diseases
May 2017 Volume 17 Number 5 p461-562 e128-e165
http://www.thelancet.com/journals/laninf/issue/current

Comment
Cholera vaccination: pregnant women excluded no more
Pedro L Moro, Lakshmi Sukumaran
Summary
Cholera is a serious dehydrating diarrhoeal disease caused by toxigenic serogroups (O1 and O139) of Vibrio cholerae, which is spread by faecal contamination of water and food. It is a disease of poverty and is closely linked to poor sanitation and lack of clean water.1 Cholera affects up to 2·8 million people and kills approximately 91 000 each year.2 Children aged younger than 5 years have the greatest incidence of disease in endemic areas. Among pregnant women, cholera can cause serious complications—namely, fetal loss, with rates varying from 2% to 36%.

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