Cancer trials in sub-Saharan Africa: Aligning research and care

PLoS Medicine
http://www.plosmedicine.org/
(Accessed 15 July 2017)

Essay
Cancer trials in sub-Saharan Africa: Aligning research and care
Satish Gopal
| published 10 Jul 2017 PLOS Medicine
https://doi.org/10.1371/journal.pmed.1002351
Summary points
:: There is an extreme scarcity of evidence to guide cancer treatment in sub-Saharan Africa (SSA), as well as major differences between SSA and resource-rich settings regarding cancer treatment infrastructure.
:: A possible framework for conceptualizing cancer clinical trials in SSA is proposed, and key issues related to equipoise, innovation, and efficiency are addressed within the SSA context.
:: Strongly aligned cancer care and research agendas can generate forward progress for cancer treatment in the region and globally impactful clinical science that can change treatment paradigms even in resource-rich settings.