September 2017, Vol 171, No. 9, Pages 823-924
Public Health and Economic Consequences of Vaccine Hesitancy for Measles in the United States
Nathan C. Lo, BS; Peter J. Hotez, MD, PhD
JAMA Pediatr. 2017;171(9):887-892. doi:10.1001/jamapediatrics.2017.1695
Question How does vaccine hesitancy affect annual measles cases and economic costs in the United States?
Findings In this modeling study of children (age 2-11 years), a 5% reduction in measles, mumps, and rubella vaccination coverage resulted in a 3-fold increase in annual measles cases with an additional US$2.1 million in public sector costs.
Meaning Even small declines in vaccination coverage in children owing to vaccine hesitancy may have substantial public health and economic consequences that will be larger when considering unvaccinated infants, adolescents, and adults.