The Impact of Hepatitis B Vaccine Failure on Long-term Natural Course of Chronic Hepatitis B Virus Infection in Hepatitis B e Antigen–Seropositive Children

Journal of Infectious Diseases
Volume 216, Issue 6   15 September 2017
https://academic.oup.com/jid/issue

VIRUSES
The Impact of Hepatitis B Vaccine Failure on Long-term Natural Course of Chronic Hepatitis B Virus Infection in Hepatitis B e Antigen–Seropositive Children
Chi-San Tai; Jia-Feng Wu; Huey-Ling Chen; Yen-Hsuan Ni; Hong-Yuan Hsu
The Journal of Infectious Diseases, Volume 216, Issue 6, 15 September 2017, Pages 662–669, https://doi.org/10.1093/infdis/jix339
Vaccine failure with chronic hepatitis B virus (HBV) infection still develops in children after universal hepatitis B immunization. Vaccine failure HBV-carrier children were associated with delayed hepatitis B e antigen seroconversion, and more HBV genotype C infection.