Incidence rate of breakthrough varicella observed in healthy children after 1 or 2 doses of varicella vaccine: Results from a meta-analysis

American Journal of Infection Control
January 2018 Volume 46, Issue 1, p1-122, e1-e12
http://www.ajicjournal.org/current

Major Article
Incidence rate of breakthrough varicella observed in healthy children after 1 or 2 doses of varicella vaccine: Results from a meta-analysis
Although extensive varicella vaccination coverage has been reported in many countries, breakthrough varicella (BV) still occurs in healthy children. We performed a meta-analysis to understand whether 2 varicella vaccine doses are needed in children and, if so, to determine the best time to vaccinate… Two doses of varicella vaccine are more effective than a single dose, and 3-4 years between the first and second vaccinations may achieve higher efficacy.
Sui Zhu, Fangfang Zeng, Lan Xia, Hong He, Juying Zhang
e1–e7
Published online: September 18, 2017