Relative Vaccine Effectiveness of High-Dose Versus Standard-Dose Influenza Vaccines Among Veterans Health Administration Patients

Journal of Infectious Diseases
Volume 217, Issue 11, 5 May 2018
https://academic.oup.com/jid/issue/217/1

Editor’s Choice
Relative Vaccine Effectiveness of High-Dose Versus Standard-Dose Influenza Vaccines Among Veterans Health Administration Patients
Yinong Young-Xu; Robertus Van Aalst; Salaheddin M Mahmud; Kenneth J Rothman; Julia Thornton Snider
Using the prior event rate ratio approach, which controls for confounding from unmeasured variables, we found that, in protecting senior Veterans Health Administration patients against influenza- or pneumonia-associated hospitalization, a high-dose influenza vaccine was more effective than a standard-dose vaccine.