Annals of Internal Medicine
1 May 2018 Vol: 168, Issue 9
Evaluating Vaccination Strategies for Zika Virus in the Americas
David P. Durham, PhD; Meagan C. Fitzpatrick, PhD; Martial L. Ndeffo-Mbah, PhD; Alyssa S. Parpia, MPH; Nelson L. Michael, MD, PhD; Alison P. Galvani, PhD
A Zika vaccine of moderate to high efficacy may virtually eliminate prenatal infections through a combination of direct protection and transmission reduction. Efficiency of age-specific targeting of Zika vaccination depends on the timing of future outbreaks.