PLoS Neglected Tropical Diseases
(Accessed 2 Jun 2018)
A serologic study of dengue in northwest Ethiopia: Suggesting preventive and control measures
Getachew Ferede, Moges Tiruneh, Ebba Abate, Yitayih Wondimeneh, Demekech Damtie, Endalamaw Gadisa, Rawleigh Howe, Abraham Aseffa, Belay Tessema
Research Article | published 31 May 2018 PLOS Neglected Tropical Diseases
Despite dengue is currently one of the leading causes of arboviral diseases in the globe, it is unrecognized and underreported in Africa, particularly in Ethiopia. Thus, we conducted a cross-sectional study among febrile patients who were attending health institutions to document seroprevalence and associated risk factors of DENV infection in the country. The study illustrated the presence of antibodies against DENV infection for the first time in both study areas, an awaking message for those who were involved in health sectors. Most of the active DENV transmission was found in monsoon and post-monsoon periods with a peak in the month of August. In multivariate analysis residence, occupational status and seasonal variations were significantly associated with the prevalence of anti-DENV IgM seropositivity. Moreover, individuals who lack a mosquito net use and the presence of uncovered water storages either indoors or outdoors were identified as the risk factors of DENV infection. Therefore, we recommend that preventive measures should be considered. Moreover, nationwide surveillance should be carried out at large.