Reproducibility crisis in science or unrealistic expectations?

EMBO Reports
01 June 2018; volume 19, issue 6
http://embor.embopress.org/content/19/6?current-issue=y

Opinion
Reproducibility crisis in science or unrealistic expectations?
The reproducibility crisis in biomedical research has spurred much debate about the causes of the failure to validate experimental results. But the discussion may be overlooking one crucial factor that is inherent to research with low sample sizes: random variation.
EMBO Reports (2018) 19: e46008
Thiago FA França, José Maria Monserrat