Meningococcal B Vaccine Immunogenicity in Children With Defects in Complement and Splenic Function

Pediatrics
September 2018, VOLUME 142 / ISSUE 3
http://pediatrics.aappublications.org/content/142/3?current-issue=y

Meningococcal B Vaccine Immunogenicity in Children With Defects in Complement and Splenic Function
Federico Martinón-Torres, Ewa Bernatowska, Anna Shcherbina, Susanna Esposito, Leszek Szenborn, Magda Campins Marti, Stephen Hughes, Saul N. Faust, Luis I. Gonzalez-Granado, Ly-Mee Yu, Diego D’Agostino, Marco Calabresi, Daniela Toneatto, Matthew D. Snape
Pediatrics Sep 2018, 142 (3) e20174250; DOI: 10.1542/peds.2017-4250
Children with complement deficiency respond less well to immunization with 4CMenB than healthy children in the control category; surveillance for vaccine failures is required to determine the significance of this.