Announcements

Announcements

AERAS  [to 13 Oct 2018 ]
http://www.aeras.org/pressreleases
No new digest content identified.
 
BMGF – Gates Foundation  [to 13 Oct 2018 ]
http://www.gatesfoundation.org/Media-Center/Press-Releases
No new digest content identified.
 
Bill & Melinda Gates Medical Research Institute    [to 13 Oct 2018 ]
https://www.gatesmri.org/
The Bill & Melinda Gates Medical Research Institute is a non-profit biotech organization. Our mission is to develop products to fight malaria, tuberculosis, and diarrheal diseases—three major causes of mortality, poverty, and inequality in developing countries. The world has unprecedented scientific tools at its disposal; now is the time to use them to save the lives of the world’s poorest people
No new digest content identified.
 
CARB-X   [to 13 Oct 2018 ]
https://carb-x.org/
CARB-X is a non-profit public-private partnership dedicated to accelerating antibacterial research to tackle the global rising threat of drug-resistant bacteria.
No new digest content identified.
 
CEPI – Coalition for Epidemic Preparedness Innovations  [to 13 Oct 2018 ]
http://cepi.net/
No new digest content identified.
 
EDCTP    [to 13 Oct 2018 ]
http://www.edctp.org/
The European & Developing Countries Clinical Trials Partnership (EDCTP) aims to accelerate the development of new or improved drugs, vaccines, microbicides and diagnostics against HIV/AIDS, tuberculosis and malaria as well as other poverty-related and neglected infectious diseases in sub-Saharan Africa, with a focus on phase II and III clinical trials
8 October 2018
Ebola emergency call September 2018: research response to the DRC outbreak
On 3 September 2018, EDCTP launched a €2.25 million emergency funding initiative in response to Ebola virus disease (EVD) outbreaks in the Democratic Republic of the Congo (DRC). This emergency call was open for proposals for seven days…
Approved projects from the call
Five consortia were informed (ahead of finalising the grant agreement preparations) that the projects funded under this initiative may commence immediately with the date of submission of their respective proposals as the earliest possible starting date.
:: The AdjustEBOVGP-Dx project aims to develop biochemical treatments that adjust native Ebola virus glycoproteine (EBOV GP) in patient sample as a target for rapid diagnostic testing. The project is expected to yield the first prototypes of rapid diagnostic tests for the duo-detection of EBOV and Marburg virus (MARV).
:: The EPIRISK-Ebov study will assess the EBOV cross-sectional seroprevalence as well as the incidence of a longitudinal seroconversion. The presence of EBOV and possible additional pathogens will be determined via pan-domain molecular approaches following a pathogen enrichment method.
:: The CAPA-CT II project aims to generate knowledge relevant to the potential spread of the EVD outbreak in Democratic Republic of the Congo (DRC) to the Republic of Uganda. The project also intends generate local knowledge for interpretation of pharmacokinetic data generated through MEURI [Monitored Emergency Use of Unregistered Interventions], drug interactions with antiretroviral drugs and to inform future treatment optimisation approaches.
:: The PEAU-EBOV-DRC aims to improve the management, both therapeutic and diagnostic, of patients with EVD through the application of an optimal standard of care, by focussing on 2 out 12 research priorities identified by the DRC Ministry of Health: 1) to coordinate the design and support the rapid implementation of efficacy trials to evaluate therapeutic product candidates, and 2) to strengthen the DRC’s capacity for the safe handling, diagnosis and reporting of major diseases caused by haemorrhagic fever viruses.
:: The MobEBO-DRC project aims to train teams in DRC and expand capacity for recombinase polymerase amplification (RPA) testing to the differentials recommended by the WHO. The project will use a mobile suitcase laboratory for EBOV point-of-care  detection at Ebola treatment centers which was successfully implemented in Guinea during the large EVD outbreak in West-Africa 2014-2015…
 
 
Emory Vaccine Center    [to 13 Oct 2018 ]
http://www.vaccines.emory.edu/
No new digest content identified.
 
 
European Medicines Agency  [to 13 Oct 2018 ]
http://www.ema.europa.eu/ema/
News and press releases
No new digest content identified.
 
 
European Vaccine Initiative  [to 13 Oct 2018 ]
http://www.euvaccine.eu/news-events
08 October 2018
TRANSVAC: European Training in Vaccinology
Second call for training modules now open
 
 
FDA [to 13 Oct 2018 ]
http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/default.htm
October 09, 2018
Statement from FDA Commissioner Scott Gottlieb, M.D., on new efforts to advance the development of generic copies of complex drugs to improve patient access to medicines
 
 
Fondation Merieux  [to 13 Oct 2018 ]
http://www.fondation-merieux.org/
Mérieux Foundation co-organized event
Dengue pre-vaccination screening based on serostatus: rapid tests and implementation strategies
January 14 – 16, 2019 – Les Pensières Center for Global Helath, Veyrier du Lac (France)
 
 
Gavi [to 13 Oct 2018 ]
https://www.gavi.org/
11 October 2018
Democratic Republic of Congo launches major vaccination drive
[See Milestones above for details]
 
 
11 October 2018
Government of Brazil signs grant agreement for US$ 20 million in support to IFFIm
 
 
GHIT Fund   [to 13 Oct 2018 ]
https://www.ghitfund.org/newsroom/press
GHIT was set up in 2012 with the aim of developing new tools to tackle infectious diseases that devastate the world’s poorest people. Other funders include six Japanese pharmaceutical
No new digest content identified.
 
 
Global Fund [to 13 Oct 2018 ]
http://www.theglobalfund.org/en/news/?topic=&type=NEWS;&country
No new digest content identified.
 
 
Hilleman Laboratories   [to 13 Oct 2018 ]
http://www.hillemanlabs.org/
No new digest content identified.
 
 
Human Vaccines Project   [to 13 Oct 2018 ]
http://www.humanvaccinesproject.org/media/press-releases/
Event
Towards a Universal Influenza Vaccine: Lessons from the Great Influenza Pandemic of 1918 to Now
November 15-16, 2018 I Nashville, TN
The Human Vaccines Project is hosting a scientific summit featuring prominent researchers and thought leaders to discuss cutting-edge influenza research. The 2-day meeting will bring together leading scientists, clinicians and public health specialists including: John Barry, James E. Crowe, Jr., Senator Bill Frist, and Laurie Garrett.  Find a full agenda at:
www.humanvaccinesproject.org/talks/universalinfluenzavaccinesummit
 
 
IAVI  [to 13 Oct 2018 ]
https://www.iavi.org/
October 9, 2018
IAVI Announces Clinical Trial of Next-Generation HIV Vaccine Candidate Designed to Induce Antibodies to Block HIV Infection
Phase I trial to evaluate safety and immunogenicity of vaccine candidate engineered to elicit targeted immune response against HIV
[See Milestones above for details]
 
 
IFFIm
http://www.iffim.org/library/news/press-releases/
11 October 2018
Government of Brazil signs grant agreement for US$ 20 million in support to IFFIm
Becomes second BRICS donor to support accelerated funding for  Gavi immunisation programmes in the world’s poorest countries.
London – 11 October 2018 – The Government of Brazil formally approved today a grant of US$ 20 million to the International Finance Facility for Immunisation, or IFFIm, which will accelerate the availability of funding for immunisation programmes supported by Gavi, the Vaccine Alliance. Brazil’s commitment of $1 million per year for 20 years makes it the 10th donor to IFFIm overall and the second BRICS donor after South Africa.
The approval today follows a meeting at the time of the annual United Nations General Assembly in New York City last month, when Brazil’s Minister of Health, Gilberto Occhi, Dr. Seth Berkley, CEO of Gavi, and Christopher Egerton-Warburton, a member of the IFFIm Board of Directors, met to discuss the country’s commitment.
“Brazil’s grant is important not only because it will provide additional funding for immunisation in the poorest countries,” said Cyrus Ardalan, Chair of IFFIm’s Board of Directors. “It also sends a powerful message that Brazil can play a leading role in efforts to solve some of the biggest public health challenges around the globe.”…
 
 
IVAC  [to 13 Oct 2018 ]
https://www.jhsph.edu/research/centers-and-institutes/ivac/index.html
October 2018
Dr. Kate O’Brien appointed Director of WHO’s Department of Immunization, Vaccines and Biologicals
Dr. William Moss named Interim Executive Director, IVAC
[See Milestones above for details]
 
 
IVI   [to 13 Oct 2018 ]
http://www.ivi.int/
[Undated]
‘The Euvichol story’ published in Vaccine
“The Euvichol Story – Development and licensure of a safe, effective and affordable oral cholera vaccine through global public private partnerships” spearheaded by the International Vaccine Institute (IVI), has been published in Vaccine by Elsevier.
The Euvichol Story published on October 9, 2018 in the journal Vaccine describes IVI’s efforts and public-private partnerships with collaborators in Sweden, Vietnam, India, South Korea and the U.S. to increase the supply of affordable oral cholera vaccines; as well as IVI’s collaboration with many other stakeholders to shape the demand of affordable OCVs globally…
 
 
JEE Alliance  [to 13 Oct 2018 ]
https://www.jeealliance.org/
No new digest content identified.
 
 
MSF/Médecins Sans Frontières  [to 13 Oct 2018 ]
http://www.msf.org/
Selected Press Releases/Statements
Central African Republic
With improved access, malaria and malnutrition cases sharply rise in Bossangoa
Project Update 12 Oct 2018
 
 
DRC 2018 Ebola outbreaks
“Ebola is about human beings and trust”
Interview 12 Oct 2018
Dr Hilde De Clerck is one of MSF’s most experienced Ebola doctors and has been managing outbreaks of Ebola and similar viruses for more than 10 years. Hilde has just returned from North Kivu, in eastern Democratic Republic of Congo (DRC), where the latest outbreak of Ebola has proven hard to control. New drugs, which might help cure those who have contracted the virus, are available, but offering and administering these drugs, says Hilde, is not as easy as it may seem….
 
 
Indonesia
Getting healthcare and safe water to remote areas in Central Sulawesi
Project Update 11 Oct 2018
 
 
DRC 2018 Ebola outbreaks
Crisis update – October 2018
 
 
NIH  [to 13 Oct 2018 ]
http://www.nih.gov/news-events/news-releases
October 12, 2018
NIH programs shed light on gene variants and their connections to health and disease
ClinGen and ClinVar address major obstacles to genomic medicine.
Programs supported by the National Institutes of Health are establishing which genes and genomic variants play a role in human disease, enabling their use in genomic medicine and research. NIH’s Clinical Genome Resource (ClinGen (link is external)) and ClinVar programs address a major barrier to incorporating genomic medicine into healthcare, which is a lack of evidence about the relationship between gene variants and diseases. A special issue of Human Mutation (link is external), published on Oct. 12, highlights the broad array of advances made through these programs, which work in concert to advance knowledge connecting human genomic variation to human health…

Scientists develop novel vaccine for Lassa fever and rabies
October 11, 2018 — A novel vaccine designed to protect people from both Lassa fever and rabies showed promise in preclinical testing, according to new research published in Nature Communications. The investigational vaccine, called LASSARAB, was developed and tested by scientists at Thomas Jefferson University in Philadelphia; the University of Minho in Braga, Portugal; the University of California, San Diego; and the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health…

Gene mutation points to new way to fight diabetes, obesity, heart disease
October 9, 2018 — Finding could provide the basis for drug therapies.
 
 
PATH  [to 13 Oct 2018 ]
https://www.path.org/media center/
No new digest content identified.
 
 
Sabin Vaccine Institute  [to 13 Oct 2018 ]
http://www.sabin.org/updates/pressreleases
No new digest content identified. 
 
 
UNAIDS [to 13 Oct 2018 ]
http://www.unaids.org/en
News   12 October 2018
Francophone parliamentary network reiterates its commitment to respond to AIDS, tuberculosis and malaria
The Parliamentary Network to Fight AIDS, Tuberculosis and Malaria reaffirmed its commitment to increase funding to end the three diseases at its annual meeting in Lomé, Togo, held on 4 and 5 October. The network committed to urge the heads of state and government of the Francophonie to advocate for increased funding during the sixth replenishment conference of the Global Fund to Fight AIDS, Tuberculosis and Malaria, which will be held in Lyon, France, in October 2019.
 
 
UNICEF  [to 13 Oct 2018 ]
https://www.unicef.org/media/press-releases
Selected Press Releases/Reports/Statements
Press release
80 per cent of school children returned to school in Ebola-affected areas of the Democratic Republic of the Congo
12/10/2018
 
Press release
Yemen: UNICEF’s Emergency Cash Transfers for 9 million people resume
 
 
Vaccine Confidence Project  [to 13 Oct 2018 ]
http://www.vaccineconfidence.org/
Vaccine Confidence Project – Confidence Commentary
Dramatic drop in public confidence after Philippines dengue vaccine controversy
Heidi Larson | 12 Oct, 2018
The Philippines’ highly politicised response to newly-reported risks of a dengue vaccine led to a dramatic drop in public trust in vaccines overall, in new research published in Human Vaccines & Immunotherapeutics.
Led by the Vaccine Confidence Project at the London School of Hygiene & Tropical Medicine (LSHTM), the study measured the impact of the Dengvaxia crisis on overall vaccine confidence before and after the manufacturer highlighted a risk associated with the vaccine and the associated political fallout.
The study of 1,500 participants revealed a dramatic drop in vaccine confidence, from the majority (93%) “strongly agreeing” that vaccines are important in 2015 to a third (32%) in 2018. The researchers say the findings highlight the importance of identifying gaps or breakdowns in public confidence in vaccines in order to rebuild trust before a pandemic strikes…
 
 
Vaccine Education Center – Children’s Hospital of Philadelphia  [to 13 Oct 2018 ]
http://www.chop.edu/centers-programs/vaccine-education-center
No new digest content identified.
 
 
Wellcome Trust  [to 13 Oct 2018 ]
https://wellcome.ac.uk/news
News / Published: 11 October 2018
Wellcome funding puts digital technology at the heart of medical research
Spotting brain injuries from babies’ brainwaves, and predicting the best way to tailor stroke care to individual patients are two examples of how digital technology is transforming health. The projects are funded through our Innovator Awards.
 
News / Published: 11 October 2018
Wellcome’s Berlin office will focus on global health
Wellcome is planning to open a small office in Berlin so that we can work more closely with our international partners, tackling global health challenges such as epidemic preparedness and drug-resistant infections.
The German capital is a leading international centre for global health, research, innovation and culture. As a global foundation, Wellcome wants to be part of this exciting hub, and we want to explore new ideas and opportunities…
 
 
The Wistar Institute   [to 13 Oct 2018 ]
https://www.wistar.org/news/press-releases
Press Release   Oct. 10, 2018
Synthetic DNA Vaccine Against Ebola Virus Shows Potent and Long-term Efficacy in Preclinical Studies
DNA vaccines are safe and offer an alternative to traditional vaccines for immunization of vulnerable at-risk populations.
 
Press Release  Oct. 8, 2018
Mechanism of Resistance to Novel Targeted Therapy for Ovarian Cancer Identified
BCL2 inhibitors may provide a novel therapeutic strategy to prevent or overcome acquired resistance to EZH2 inhibitors in ARID1A-mutant cancers.
 
 
World Organisation for Animal Health (OIE)   [to 13 Oct 2018 ]
http://www.oie.int/en/for-the-media/press-releases/2018/
No new digest content identified.
 
 
BIO    [to 13 Oct 2018 ]
https://www.bio.org/insights/press-release
No new digest content identified.
 
 
DCVMN – Developing Country Vaccine Manufacturers Network  [to 13 Oct 2018 ]
http://www.dcvmn.org/
29 October 2018 to 31 October 2018
19th DCVMN Annual General Meeting
Kunming / China
 
 
IFPMA   [to 13 Oct 2018 ]
http://www.ifpma.org/resources/news-releases/
No new digest content identified.
 
 
PhRMA    [to 13 Oct 2018 ]
http://www.phrma.org/press-room
No new digest content identified.