December 4, 2018, Vol 320, No. 21, Pages 2171-2280
Oncology in Transition – Changes, Challenges, and Opportunities
Deborah Schrag, MD, MPH; Ethan Basch, MD, MSc
Contemporary challenges and changes in the field of oncology reflect and often magnify medicine more broadly. Morbidity and mortality are often substantial, treatment is expensive, and management is complex necessitating interdisciplinary coordination across every field of medicine. The recent emergence of immunotherapy and adoptive cellular therapy has generated tremendous excitement because these approaches can sometimes achieve cure or durable responses, even in the setting of advanced cancer.