New England Journal of Medicine
December 13, 2018 Vol. 379 No. 24
History of Medicine: Influenza Cataclysm, 1918
David M. Morens, M.D., and Jeffery K. Taubenberger, M.D., Ph.D.
This year marks the centennial of an influenza pandemic that killed 50 million to 100 million people globally — arguably the single deadliest event in recorded human history. Evidence suggests that another pandemic at least as severe may occur one day.