T Cell Memory to Vaccination

Vaccines — Open Access Journal
(Accessed 15 Dec 2018)

Open Access  Editorial
T Cell Memory to Vaccination
by Stephen M Todryk
Vaccines 2018, 6(4), 84; https://doi.org/10.3390/vaccines6040084 (registering DOI) – 14 December 2018
Most immune responses associated with vaccination are controlled by specific T cells of a CD4+ helper phenotype which mediate the generation of effector antibodies, cytotoxic T lymphocytes (CTLs), or the activation of innate immune effector cells. A rapidly growing understanding of the generation, maintenance, activity, and measurement of such T cells is leading to vaccination strategies with greater efficacy and potentially greater microbial coverage