Assessing the sensitivity of the polio environmental surveillance system

PLoS One
http://www.plosone.org/
[Accessed 5 Jan 2019]

Assessing the sensitivity of the polio environmental surveillance system
The polio environmental surveillance (ES) system has been an incredible tool for advancing polio eradication efforts because of its ability to highlight the spatial and temporal extent of poliovirus circulation. While ES often outperforms, or is more sensitive than AFP surveillance, the sensitivity of the ES system has not been well characterized. Fundamental uncertainty of ES site sensitivity makes it difficult to interpret results from ES, particularly negative results.
Steve J. Kroiss, Maiwand Ahmadzai, Jamal Ahmed, Muhammad Masroor Alam, Guillaume Chabot-Couture, Michael Famulare, Abdirahman Mahamud, Kevin A. McCarthy, Laina D. Mercer, Salman Muhammad, Rana M. Safdar, Salmaan Sharif, Shahzad Shaukat, Hemant Shukla, Hil Lyons
Research Article | published 28 Dec 2018 PLOS ONE
https://doi.org/10.1371/journal.pone.0208336