Middle East Respiratory Syndrome Vaccine Candidates: Cautious Optimism

Viruses
Volume 11, Issue 1 (January 2019)
https://www.mdpi.com/1999-4915/11/1

Open Access  Review
Middle East Respiratory Syndrome Vaccine Candidates: Cautious Optimism
by Craig Schindewolf and Vineet D. Menachery
Viruses 2019, 11(1), 74; https://doi.org/10.3390/v11010074
Received: 18 December 2018 / Revised: 10 January 2019 / Accepted: 12 January 2019 / Published: 17 January 2019
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Abstract
Efforts towards developing a vaccine for Middle East respiratory syndrome coronavirus (MERS-CoV) have yielded promising results. Utilizing a variety of platforms, several vaccine approaches have shown efficacy in animal models and begun to enter clinical trials. In this review, we summarize the current progress towards a MERS-CoV vaccine and highlight potential roadblocks identified from previous attempts to generate coronavirus vaccines