New England Journal of Medicine
February 7, 2019 Vol. 380 No. 6
Risk Compensation and Clinical Decision Making — The Case of HIV Preexposure Prophylaxis
Julia L. Marcus, Ph.D., M.P.H., Kenneth A. Katz, M.D., M.S.C.E., Douglas S. Krakower, M.D.,and Sarah K. Calabrese, Ph.D.
Uptake of preexposure prophylaxis (PrEP) for HIV has been limited for multiple reasons, including low awareness. Clinicians’ concerns that an increased sense of protection will lead to greater risk taking among PrEP users are another important factor.