Clinical use of current polygenic risk scores may exacerbate health disparities

Nature Genetics
Volume 51 Issue 4, April 2019
https://www.nature.com/ng/volumes/51/issues/4

Perspective | 29 March 2019
Clinical use of current polygenic risk scores may exacerbate health disparities
This Perspective discusses scientific and ethical considerations regarding the clinical use of polygenic risk scores, highlighting the pressing need to diversify cohorts for genetic studies beyond European-ancestry populations.
Alicia R. Martin, Masahiro Kanai […]  & Mark J. Daly