Sequencing-based methods and resources to study antimicrobial resistance

Nature Reviews Genetics
Volume 20 Issue 6, June 2019
https://www.nature.com/nrg/volumes/20/issues/6

 

Review Article | 18 March 2019
Sequencing-based methods and resources to study antimicrobial resistance
Next-generation sequencing has improved the identification and characterization of antimicrobial resistance. Focusing on sequence-based discovery of antibiotic resistance genes, this Review discusses computational strategies and resources for resistance gene identification in genomic and metagenomic samples, including recent deep-learning approaches.
Manish Boolchandani, Alaric W. D’Souza & Gautam Dantas