T cell-mediated immunity to malaria

Nature Reviews Immunology
Volume 19 Issue 7, July 2019
https://www.nature.com/nri/volumes/19/issues/7

 

Review Article | 02 April 2019
T cell-mediated immunity to malaria
John Harty and colleagues explain how different subsets of CD4+ T cells, CD8+ T cells and γδ T cells respond to the Plasmodium parasites that cause malaria. They discuss the major challenges that need to be overcome in order to harness T cell responses for malaria vaccines and therapies.
Samarchith P. Kurup, Noah S. Butler & John T. Harty