A vaccine-induced gene expression signature correlates with protection against SIV and HIV in multiple trials

Science Translational Medicine
28 August 2019 Vol 11, Issue 507
https://stm.sciencemag.org/

 

Research Articles
A vaccine-induced gene expression signature correlates with protection against SIV and HIV in multiple trials
By Philip K. Ehrenberg, Shida Shangguan, Biju Issac, Galit Alter, Aviva Geretz, Taisuke Izumi, Christopher Bryant, Michael A. Eller, Frank Wegmann, Richard Apps, Matthew Creegan, Diane L. Bolton, Rafick P. Sekaly, Merlin L. Robb, Robert A. Gramzinski, Maria G. Pau, Hanneke Schuitemaker, Dan H. Barouch, Nelson L. Michael, Rasmi Thomas
Science Translational Medicine28 Aug 2019 Restricted Access
A gene signature in B cells associates with protective efficacy of different vaccine regimens against SIV and HIV infection.