Journal of Travel Medicine
Volume 26, Issue 6, 2019
What is the prospect of a safe and effective dengue vaccine for travellers?
Anna P Durbin, MD, Duane J Gubler, ScD
Journal of Travel Medicine, Volume 26, Issue 6, 2019, tay153, https://doi.org/10.1093/jtm/tay153
Dengue affects hundreds of millions of persons each year and is a risk for travellers to dengue-endemic regions. The first licensed dengue vaccine is approved for use only in persons who are known to have had previous dengue infection, limiting its potential for use in travellers. Two other dengue vaccines are currently in Phase 3 clinical trials, with preliminary efficacy results expected soon. These vaccines differ from the currently licensed vaccine and, should they demonstrate efficacy, may offer the possibility of a dengue vaccine for travellers.