Prevalence of Immunodeficiency in Children With Invasive Pneumococcal Disease in the Pneumococcal Vaccine EraA Systematic Review

JAMA Pediatrics
November 2019, Vol 173, No. 11, Pages 1007-1115
http://archpedi.jamanetwork.com/issue.aspx

 

Review
Prevalence of Immunodeficiency in Children With Invasive Pneumococcal Disease in the Pneumococcal Vaccine EraA Systematic Review
Coen Butters, BMed, DCH; Linny Kimly Phuong, BPharm(Hons), MBBS, DCH, MPH; Theresa Cole, BM, MRCPCH, PhD, FRACP; et al.
JAMA Pediatr. 2019;173(11):1084-1094. doi:10.1001/jamapediatrics.2019.3203
This systematic review of 17 studies assesses risk of primary immunodeficiency in children presenting with invasive pneumococcal disease with no other predisposing condition.