November 19, 2019, Vol 322, No. 19, Pages 1839-1932
Complexity in Assessing the Benefit vs Risk of Vaccines – Experience With Rotavirus and Dengue Virus Vaccines
H. Cody Meissner, MD
JAMA. 2019;322(19):1861-1862. doi:10.1001/jama.2019.16206
This Viewpoint uses experience with rotavirus vaccine–induced intussusception and dengue virus vaccine–induced shock syndrome to discuss issues of disease prevalence and severity underlying recommendations the vaccines be used widely, and it reviews the systems in place to monitor vaccine safety that broadly favor vaccine benefits over risks to individuals and society.