A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses

Science
06 December 2019 Vol 366, Issue 6470
http://www.sciencemag.org/current.dtl

 

Research Articles
A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses
By Jon M. Steichen, Ying-Cing Lin, Colin Havenar-Daughton, Simone Pecetta, Gabriel Ozorowski, Jordan R. Willis, Laura Toy, Devin Sok, Alessia Liguori, Sven Kratochvil, Jonathan L. Torres, Oleksandr Kalyuzhniy, Eleonora Melzi, Daniel W. Kulp, Sebastian Raemisch, Xiaozhen Hu, Steffen M. Bernard, Erik Georgeson, Nicole Phelps, Yumiko Adachi, Michael Kubitz, Elise Landais, Jeffrey Umotoy, Amanda Robinson, Bryan Briney, Ian A. Wilson, Dennis R. Burton, Andrew B. Ward, Shane Crotty, Facundo D. Batista, William R. Schief
Science06 Dec 2019 Restricted Access
A repertoire-guided germline-targeting approach for development of broadly neutralizing anti-HIV antibodies is explored.