April 21, 2020, Vol 323, No. 15, Pages 1427-1518
Diagnostic Testing for the Novel Coronavirus
Joshua M. Sharfstein, MD; Scott J. Becker, MS; Michelle M. Mello, JD, PhD
free access has active quiz has multimedia has audio
JAMA. 2020;323(15):1437-1438. doi:10.1001/jama.2020.3864
This Viewpoint explains the technical and regulatory challenges that hampered diagnostic testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) during the early spread of infection in the US and considers the unintended consequences of making testing more widely available, including false-negative results and overtesting.
Audio Interview: Coronavirus Testing – March 16 Q&A with the CDC’s Jay Butler, MD
Clinical Review Audio: Coronavirus Disease 2019 (COVID-19) Update: PCR Testing and Shortages