April 28, 2020, Vol 323, No. 16, Pages 1529-1626
Treatment of 5 Critically Ill Patients With COVID-19 With Convalescent Plasma
Chenguang Shen, PhD; Zhaoqin Wang, PhD; Fang Zhao, PhD; et al.
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JAMA. 2020;323(16):1582-1589. doi:10.1001/jama.2020.4783
This case series describes clinical outcomes in 5 Chinese patients with laboratory-confirmed COVID-19, ARDS, and high viral loads despite antiviral treatment who were given human plasma with SARS-CoV-2 antibodies obtained from previously infected and recovered patients.