May 12, 2020, Vol 323, No. 18, Pages 1749-1862
Pharmacologic Treatments for Coronavirus Disease 2019 (COVID-19)A Review
James M. Sanders, PhD, PharmD; Marguerite L. Monogue, PharmD; Tomasz Z. Jodlowski, PharmD; et al.
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JAMA. 2020;323(18):1824-1836. doi:10.1001/jama.2020.6019
This narrative review summarizes what is currently known about how SARS-CoV-2 infects cells and causes disease as a basis for considering whether chloroquine, remdisivir and other antivirals, or other existing drugs might be effective treatment for coronavirus disease 2019 (COVID-19).