Journal of Infectious Diseases
Volume 221, Issue 11, 1 June 2020
Human Challenge Studies to Accelerate Coronavirus Vaccine Licensure
Nir Eyal, Marc Lipsitch, Peter G Smith
The Journal of Infectious Diseases, Volume 221, Issue 11, 1 June 2020, Pages 1752–1756, https://doi.org/10.1093/infdis/jiaa152
Controlled human challenge trials of SARS-CoV-2 vaccine candidates could accelerate the testing and potential rollout of efficacious vaccines, reducing the global burden of coronavirus-related mortality and morbidity. Volunteers’ net risk in such studies could be acceptable under specific conditions.