Overview of the Development, Impacts, and Challenges of Live-Attenuated Oral Rotavirus Vaccines

Vaccines — Open Access Journal
http://www.mdpi.com/journal/vaccines
(Accessed 27 June 2020)

 

Open Access Review
Overview of the Development, Impacts, and Challenges of Live-Attenuated Oral Rotavirus Vaccines
by Olufemi Samuel Folorunso and Olihile M. Sebolai
Vaccines 2020, 8(3), 341; https://doi.org/10.3390/vaccines8030341 (registering DOI) – 27 Jun 2020
Abstract
Safety, efficacy, and cost-effectiveness are paramount to vaccine development. Following the isolation of rotavirus particles in 1969 and its evidence as an aetiology of severe dehydrating diarrhoea in infants and young children worldwide, the quest to find not only an acceptable and reliabl