JBI Database of Systematic Review and Implementation Reports
June 2020 – Volume 18 – Issue 6
https://journals.lww.com/jbisrir/Pages/currenttoc.aspx

EDITORIAL
COVID-19 and One Health: shifting the paradigm in how we think about health
Henley, Phaedra
JBI Evidence Synthesis. 18(6):1154-1155, June 2020.

The Lancet
Jun 20, 2020 Volume 395 Number 10241 p1883-1948, e107-e111
https://www.thelancet.com/journals/lancet/issue/current

Editorial
Global governance for COVID-19 vaccines
The Lancet
[See Milestones/Perspectives above for full text]

The Lancet
Jun 20, 2020 Volume 395 Number 10241 p1883-1948, e107-e111
https://www.thelancet.com/journals/lancet/issue/current

Comment
The right to health must guide responses to COVID-19
Dainius Pūras, Judith Bueno de Mesquita, Luisa Cabal, Allan Maleche, Benjamin Mason Mei

The Lancet
Jun 20, 2020 Volume 395 Number 10241 p1883-1948, e107-e111
https://www.thelancet.com/journals/lancet/issue/current

Articles
Clinical impact of COVID-19 on patients with cancer (CCC19): a cohort study
Nicole M Kuderer, on behalf of the COVID-19 and Cancer Consortium
Interpretation
Among patients with cancer and COVID-19, 30-day all-cause mortality was high and associated with general risk factors and risk factors unique to patients with cancer. Longer follow-up is needed to better understand the effect of COVID-19 on outcomes in patients with cancer, including the ability to continue specific cancer treatments.

Lancet Respiratory Medicine
Jun 2020 Volume 8 Number 6 p527-646, e43-e54
http://www.thelancet.com/journals/lanres/issue/current

Comment
Influenza immunisation in pregnancy is efficacious and safe, but questions remain
Paul Loubet, Vassilis Tsatsaris, Odile Launay

Lancet Respiratory Medicine
Jun 2020 Volume 8 Number 6 p527-646, e43-e54
http://www.thelancet.com/journals/lanres/issue/current

Tackling two pandemics: a plea on World Tuberculosis Day
Tom Wingfield, Luis E Cuevas, Peter MacPherson, Kerry A Millington, S Bertel Squire

Lancet Respiratory Medicine
Jun 2020 Volume 8 Number 6 p527-646, e43-e54
http://www.thelancet.com/journals/lanres/issue/current

Articles
Efficacy, duration of protection, birth outcomes, and infant growth associated with influenza vaccination in pregnancy: a pooled analysis of three randomised controlled trials
Saad B Omer,et al. for the BMGF Supported Maternal Influenza Immunization Trials Investigators Group
Open Access
Maternal influenza immunisation can reduce morbidity and mortality associated with influenza infection in pregnant women and young infants. We aimed to determine the vaccine efficacy of maternal influenza immunisation against maternal and infant PCR-confirmed influenza, duration of protection, and the effect of gestational age at vaccination on vaccine efficacy, birth outcomes, and infant growth up to 6 months of age…
Interpretation
The assessment of efficacy for women vaccinated before 29 weeks gestational age might have been underpowered, because the point estimate suggests that there might be efficacy despite wide CIs. Estimates of efficacy against PCR-confirmed influenza and safety in terms of adverse birth outcomes should be incorporated into any further consideration of maternal influenza immunisation recommendations.

The Milbank Quarterly
A Multidisciplinary Journal of Population Health and Health Policy

Volume 98, Issue 2 Pages: 223-617 June 2020
https://onlinelibrary.wiley.com/toc/14680009/current
Original Scholarship
Open Access
Can Social Policies Improve Health? A Systematic Review and Meta‐Analysis of 38 Randomized Trials
EMILIE COURTIN. SOOYOUNG KIM, SHANSHAN SONG, WENYA YU, PETER MUENNIG
Pages: 297-371
First Published: 19 March 2020
Policy Points
:: Social policies might not only improve economic well‐being, but also health. Health policy experts have therefore advocated for investments in social policies both to improve population health and potentially reduce health system costs.
:: Since the 1960s, a large number of social policies have been experimentally evaluated in the United States. Some of these experiments include health outcomes, providing a unique opportunity to inform evidence‐based policymaking.
:: Our comprehensive review and meta‐analysis of these experiments find suggestive evidence of health benefits associated with investments in early life, income support, and health insurance interventions. However, most studies were underpowered to detect health outcomes.

Nature Medicine
Volume 26 Issue 6, June 2020
https://www.nature.com/nm/volumes/26/issues/6

Editorial | 04 June 2020
It is not the time for science fiction
Government officials who disseminate unsupported claims about the novel coronavirus undermine public trust in science and in the public-health efforts that are essential to bringing the COVID-19 pandemic under control.

Nature Medicine
Volume 26 Issue 6, June 2020
https://www.nature.com/nm/volumes/26/issues/6

World View | 07 May 2020
Protect against market exclusivity in the fight against COVID-19
Patents and other intellectual properties could slow down the scale-up and accessibility of treatments and vaccines against COVID-19.
Ellen ’t Hoen

Nature Medicine
Volume 26 Issue 6, June 2020
https://www.nature.com/nm/volumes/26/issues/6

Perspective | 11 June 2020
Ten recommendations for supporting open pathogen genomic analysis in public health
To support progress in genomic epidemiology, a transparent, user-friendly approach is required.
Allison Black, Duncan R. MacCannell […]  & Trevor Bedford
Abstract
Increasingly, public-health agencies are using pathogen genomic sequence data to support surveillance and epidemiological investigations. As access to whole-genome sequencing has grown, greater amounts of molecular data have helped improve the ability to detect and track outbreaks of diseases such as COVID-19, investigate transmission chains and explore large-scale population dynamics, such as the spread of antibiotic resistance. However, the wide adoption of whole-genome sequencing also poses new challenges for public-health agencies that must adapt to support a new set of expertise, which means that the capacity to perform genomic data assembly and analysis has not expanded as widely as the adoption of sequencing itself. In this Perspective, we make recommendations for developing an accessible, unified informatic ecosystem to support pathogen genomic analysis in public-health agencies across income settings. We hope that the creation of this ecosystem will allow agencies to effectively and efficiently share data, workflows and analyses and thereby increase the reproducibility, accessibility and auditability of pathogen genomic analysis while also supporting agency autonomy.

New England Journal of Medicine
June 18, 2020 Vol. 382 No. 25
http://www.nejm.org/toc/nejm/medical-journal

Clinical Implications of Basic Research
Amplifying RNA Vaccine Development
Deborah H. Fuller, Ph.D., and Peter Berglund, Ph.D.
… With the emergence of the Covid-19 pandemic, an mRNA vaccine was the first to enter clinical trials, with the first volunteers receiving the vaccine within 10 weeks after the genetic sequence of SARS-CoV-2 was released (www.modernatx.com/modernas-work-potential-vaccine-against-covid-19. opens in new tab). Nucleic acid vaccines are now a major hope for solving this pandemic crisis. This comes as no surprise. From their earliest conception, nucleic acid vaccines were recognized as a possible solution for a rapid pandemic response. The need for only the sequence of a pathogen in order to generate the vaccine and its simplicity in manufacture have long been recognized as superpowers in nucleic acid vaccines with regard to the delivery of a rapid response to an emerging epidemic. The ability of self-amplifying RNA vaccines, and now trans-amplifying RNA vaccines, to provide amplified and durable production of antigen in vivo, coupled with potent inherent innate immune-stimulating properties, adds to these powers and may provide the dose-sparing (i.e., getting the same immune responses with smaller doses of vaccine) that will probably be needed to meet global demands. We can only hope that their deployment will render the Covid-19 pandemic crisis into a more manageable challenge, saving lives and decreasing morbidity.

PLoS Medicine
http://www.plosmedicine.org/
(Accessed 20 June 2020)

Antibiotic prescription practices in primary care in low- and middle-income countries: A systematic review and meta-analysis
Giorgia Sulis, Pierrick Adam, Vaidehi Nafade, Genevieve Gore, Benjamin Daniels, Amrita Daftary, Jishnu Das, Sumanth Gandra, Madhukar Pai
Research Article | published 16 Jun 2020 PLOS Medicine
https://doi.org/10.1371/journal.pmed.1003139

PLoS Medicine
http://www.plosmedicine.org/
(Accessed 20 June 2020)

The potential impact of COVID-19 in refugee camps in Bangladesh and beyond:  A modeling study
Shaun Truelove, Orit Abrahim, Chiara Altare, Stephen A. Lauer, Krya H. Grantz, Andrew S. Azman, Paul Spiegel
Research Article | published 16 Jun 2020 PLOS Medicine
https://doi.org/10.1371/journal.pmed.1003144

PLoS Neglected Tropical Diseases
http://www.plosntds.org/
(Accessed 20 June 2020)

Social marketing interventions for the prevention and control of neglected tropical diseases: A systematic review
Nathaly Aya Pastrana, Maria Lazo-Porras, J. Jaime Miranda, David Beran, L. Suzanne Suggs
Research Article | published 17 Jun 2020 PLOS Neglected Tropical Diseases
https://doi.org/10.1371/journal.pntd.0008360

PLoS One
http://www.plosone.org/
[Accessed 20 June 2020]

Recruiters’ perspectives of recruiting women during pregnancy and childbirth to clinical trials: A qualitative evidence synthesis
Vivienne Hanrahan, Katie Gillies, Linda Biesty
Research Article | published 19 Jun 2020 PLOS ONE
https://doi.org/10.1371/journal.pone.0234783

PLoS One
http://www.plosone.org/
[Accessed 20 June 2020]

Seasonal influenza vaccination in older people: A systematic review and meta-analysis of the determining factors
George N. Okoli, Otto L. T. Lam, Florentin Racovitan, Viraj K. Reddy, Christiaan H. Righolt, Christine Neilson, Ayman Chit, Edward Thommes, Ahmed M. Abou-Setta, Salaheddin M. Mahmud
Research Article | published 18 Jun 2020 PLOS ONE
https://doi.org/10.1371/journal.pone.0234702

PLoS One
http://www.plosone.org/
[Accessed 20 June 2020]

A hidden vulnerable population: Young children up-to-date on vaccine series recommendations except influenza vaccines
William K. Bleser, Daniel A. Salmon, Patricia Y. Miranda
Research Article | published 18 Jun 2020 PLOS ONE
https://doi.org/10.1371/journal.pone.0234466

PLoS One
http://www.plosone.org/
[Accessed 20 June 2020]

Improving measles vaccine uptake rates in Nigeria: An RCT evaluating the impact of incentive sizes and reminder calls on vaccine uptake
Steven Brownstone, Alison Connor, Daniel Stein

Research Article | published 18 Jun 2020 PLOS ONE
https://doi.org/10.1371/journal.pone.0233149

PNAS – Proceedings of the National Academy of Sciences of the United States of America
http://www.pnas.org/content/early/

Economic and social consequences of human mobility restrictions under COVID-19
Giovanni Bonaccorsi, Francesco Pierri, Matteo Cinelli, Andrea Flori, Alessandro Galeazzi, Francesco Porcelli, Ana Lucia Schmidt, Carlo Michele Valensise, Antonio Scala, Walter Quattrociocchi, and Fabio Pammolli
PNAS first published June 18, 2020. https://doi.org/10.1073/pnas.2007658117

PNAS – Proceedings of the National Academy of Sciences of the United States of America
http://www.pnas.org/content/early/

Vaccination as a social contract
Lars Korn, Robert Böhm, Nicolas W. Meier, and Cornelia Betsch
PNAS first published June 15, 2020. https://doi.org/10.1073/pnas.1919666117

Risk Analysis
Volume 40, Issue 6 Pages: 1111-1319 June 2020
https://onlinelibrary.wiley.com/toc/15396924/current

Original Research Articles
Understanding Risk Information Seeking and Processing during an Infectious Disease Outbreak: The Case of Zika Virus
Austin Y. Hubner, Shelly R. Hovick
Pages: 1212-1225
First Published: 17 February 2020

Science
19 June 2020 Vol 368, Issue 6497
http://www.sciencemag.org/current.dtl

In Depth
Pandemic vaccines are about to face the real test
By Jon Cohen
Science19 Jun 2020 : 1295-1296 Full Access
U.S. and global efforts are taking different approaches to key efficacy trials of candidates.
Summary
A Chinese company will turn to Brazil for help. The World Health Organization is adopting a strategy forged in a war zone during an Ebola outbreak. And the Trump administration plans to lean on existing infrastructure for testing HIV and flu vaccines. These are the disparate strategies about to be employed in the next and most important stage of the COVID-19 vaccine race: the large-scale, placebo-controlled, human trials needed to prove which of the more than 135 candidates are safe and effective.

Social Science & Medicine
Volume 253 May 2020
https://www.sciencedirect.com/journal/social-science-and-medicine/vol/253/suppl/C

Research article Open access
Social, ethical, and other value judgments in health economics modelling
Stephanie Harvard, Gregory R. Werker, Diego S. Silva
Article 112975
Highlights
:: Interviews with health economists reinforced philosophical arguments positing a role for values throughout research.
:: Values informed early modelling decisions, model assumptions, and trade-offs between
:: Values played a role in assessing consequences of error and taking action under uncertainty in the modelling process.
Abstract
Modelling is a major method of inquiry in health economics. In other modelling-intensive fields, such as climate science, recent scholarship has described how social and ethical values influence model development. However, no similar work has been done in health economics. This study explored the role of social, ethical, and other values in health economics modelling using philosophical theory and qualitative interviews in British Columbia, Canada. Twenty-two professionals working in health economics modelling were interviewed between February and May, 2019. The study findings provide support for four philosophical arguments positing an essential role for social and ethical values throughout scientific inquiry and demonstrate how these arguments apply to health economics modelling. It highlights the role of social values in informing early modelling decisions, shaping model assumptions, making trade-offs between desirable model features, and setting standards of evidence. These results point to several decisions in the modelling process that warrant focus in future health economics research, particularly that which aims to incorporate patient and public values.

Vaccine
Volume 38, Issue 28 Pages 4355-4506 (9 June 2020)
https://www.sciencedirect.com/journal/vaccine/vol/38/issue/28

Conference info Abstract only
Preparing to introduce new maternal immunizations in low- and lower-middle-income countries: A report from the Bill & Melinda Gates Foundation convening “Allies in Maternal and Newborn Care”; May 3–4, 2018
Ajoke Sobanjo-ter Meulen, Jerker Liljestrand, Joy E. Lawn, Joachim Hombach, … Keith P. Klugman
Pages 4355-4361

Vaccine
Volume 38, Issue 28 Pages 4355-4506 (9 June 2020)
https://www.sciencedirect.com/journal/vaccine/vol/38/issue/28

Discussion Open access
Gonococcal vaccines: Public health value and preferred product characteristics; report of a WHO global stakeholder consultation, January 2019
Sami L. Gottlieb, Francis Ndowa, Edward W. Hook, Carolyn Deal, … Birgitte K. Giersing
Pages 4362-4373

Vaccine
Volume 38, Issue 28 Pages 4355-4506 (9 June 2020)
https://www.sciencedirect.com/journal/vaccine/vol/38/issue/28

Research article No access
Electronic immunization registers – A tool for mitigating outbreaks of vaccine-preventable diseases in the Pacific
Meru Sheel, Ashley Tippins, Kathryn Glass, Martyn Kirk, Colleen L. Lau
Pages 4395-4398

Vaccine
Volume 38, Issue 28 Pages 4355-4506 (9 June 2020)
https://www.sciencedirect.com/journal/vaccine/vol/38/issue/28

Research article Abstract only
Routine immunization coverage in Pakistan: a survey of children under 1 year of age in community-based vaccination areas
Meghana Sreevatsava, Ashley L. Burman, Ashraf Wahdan, Rana M. Safdar, … Jamal Ahmed
Pages 4399-4404

Vaccine
Volume 38, Issue 28 Pages 4355-4506 (9 June 2020)
https://www.sciencedirect.com/journal/vaccine/vol/38/issue/28

Research article Abstract only
The contagious nature of a vaccine scare: How the introduction of HPV vaccination lifted and eroded MMR vaccination in Denmark
Mette Gørtz, Noel T. Brewer, Peter Reinhard Hansen, Mette Ejrnæs
Pages 4432-4439

Vaccine
Volume 38, Issue 28 Pages 4355-4506 (9 June 2020)
https://www.sciencedirect.com/journal/vaccine/vol/38/issue/28

Research article Abstract only
Routine immunization coverage in Pakistan: a survey of children under 1 year of age in community-based vaccination areas
Meghana Sreevatsava, Ashley L. Burman, Ashraf Wahdan, Rana M. Safdar, … Jamal Ahmed
Pages 4399-4404

Vaccine
Volume 38, Issue 28 Pages 4355-4506 (9 June 2020)
https://www.sciencedirect.com/journal/vaccine/vol/38/issue/28

Research article Abstract only
The contagious nature of a vaccine scare: How the introduction of HPV vaccination lifted and eroded MMR vaccination in Denmark
Mette Gørtz, Noel T. Brewer, Peter Reinhard Hansen, Mette Ejrnæs
Pages 4432-4439

Vaccine
Volume 38, Issue 28 Pages 4355-4506 (9 June 2020)
https://www.sciencedirect.com/journal/vaccine/vol/38/issue/28

Research article Abstract only
Immunizations at Wisconsin Pharmacies: Results of a statewide vaccine registry analysis and pharmacist survey
Philip C. Berce, Rebecca S. Bernstein, George E. MacKinnon, Sarah Sorum, … Kenneth G. Schellhase
Pages 4448-4456

Special Section on “Future of Vaccine Development”; Edited by W. Koff and T. Schenkelberg
Research article Abstract only

The future of vaccine development
Wayne C. Koff, Theodore Schenkelberg
Pages 4485-4486
Abstract
Vaccines are one of the most successful public health interventions in our history resulting in eradication of small pox, near eradication of polio and major reductions in case number and global morbidity and mortality for numerous diseases (Centers for Disease C, 1999) [1]. However, vaccine development has been less successful against complex infectious diseases, where pathogen variability and/or immune evasion mechanisms have combined to pose major obstacles, and have been unsuccessful against non-communicable diseases, including cancer, autoimmunity, allergy, neurodegenerative and metabolic diseases (Koff et al., 2013) [2]. In addition, the current state of vaccine development is an expensive, slow and laborious process, costing billions of dollars, taking decades, with less than a 10% rate of success (Pronker et al., 2013) [3]. While some vaccines, such as the smallpox vaccine approach the gold standard of life-long protection in everyone following a single immunization, other vaccines are less effective, often requiring multiple immunizations, being less effective to populations most susceptible to disease such as infants, the elderly, and those living in the developing world. There is clearly an urgent need to determine ways to improve not just the effectiveness of the vaccines themselves but also the very processes by which they are developed.

Vaccines — Open Access Journal
http://www.mdpi.com/journal/vaccines
(Accessed 20 June 2020)

Open Access Article
Trends, Coverage and Influencing Determinants of Influenza Vaccination in the Elderly: A Population-Based National Survey in Spain (2006–2017)
by Silvia Portero de la Cruz and Jesús Cebrino
Vaccines 2020, 8(2), 327; https://doi.org/10.3390/vaccines8020327 – 19 Jun 2020
Abstract
Influenza is a significant public health problem and the elderly are at a greater risk of contracting the disease. The vaccination coverage of the elderly is below the Spanish target of 65% for each influenza season. The aims of this study were to report the coverage of influenza vaccination in Spain among the population aged ≥65 years and high-risk groups for suffering chronic diseases, to analyze the time trends from 2006 to 2017 and to identify the factors which affect vaccination coverage. A nationwide cross-sectional study was conducted including 20,753 non-institutionalized individuals aged ≥65 years who had participated in the Spanish National Health Surveys in 2006, 2011/2012, and 2017. Sociodemographic, health-related variables, and influenza vaccination data were used. A logistic regression analysis was performed to determine the variables associated with influenza vaccination. Influenza vaccination coverage was 60%. By chronic condition, older people with high cholesterol levels and cancer had the lowest vaccination coverage (62.41% and 60.73%, respectively). This coverage declined from 2006 to 2017 in both groups. Higher influenza vaccination was associated with males, Spanish nationality, normal social support perceived, polypharmacy, worse perceived health, participation in other preventive measures, and increasing age and the number of chronic diseases.

Value in Health
June 2020 Volume 23, Issue 6, p677-826
https://www.valueinhealthjournal.com/issue/S1098-3015(20)X0008-8

ISPOR REPORT
Defining Patient Engagement in Research: Results of a Systematic Review and Analysis: Report of the ISPOR Patient-Centered Special Interest Group
Rachel L. Harrington, Maya L. Hanna, Elisabeth M. Oehrlein, Rob Camp, Russell Wheeler, Clarissa Cooblall, Theresa Tesoro, Amie M. Scott, Rainald von Gizycki, Francis Nguyen, Asha Hareendran, Donald L. Patrick, Eleanor M. Perfetto
p677–688
Published online: May 23, 2020

From Google Scholar & other sources: Selected Journal Articles, Newsletters, Dissertations, Theses, Commentary

No new digest content identified.

Media/Policy Watch
This watch section is intended to alert readers to substantive news, analysis and opinion from the general media and selected think tanks and similar organizations on vaccines, immunization, global public health and related themes. Media Watch is not intended to be exhaustive, but indicative of themes and issues CVEP is actively tracking. This section will grow from an initial base of newspapers, magazines and blog sources, and is segregated from Journal Watch above which scans the peer-reviewed journal ecology.
We acknowledge the Western/Northern bias in this initial selection of titles and invite suggestions for expanded coverage. We are conservative in our outlook in adding news sources which largely report on primary content we are already covering above. Many electronic media sources have tiered, fee-based subscription models for access. We will provide full-text where content is published without restriction, but most publications require registration and some subscription level.

The Atlantic
http://www.theatlantic.com/magazine/
Accessed 20 June 2020
[No new, unique, relevant content]

BBC
http://www.bbc.co.uk/
Accessed 20 June 2020
[No new, unique, relevant content]

The Economist
http://www.economist.com/
Accessed 20 June 2020
Geopolitics
The new world disorder
If America pulls back from global institutions, other powers must step forward

Financial Times
http://www.ft.com/home/uk
Accessed 20 June 2020
Coronavirus treatment
Europeans discuss deal to access potential J&J coronavirus vaccine
European countries are lining up a deal to secure a possible Covid-19 vaccine from US company Johnson & Johnson, marking the latest move in an intensifying international battle to secure supplies of any coronavirus treatments that emerge.
Both the European Commission and a separate quartet of EU member states comprising Germany, France, Italy and the Netherlands have held talks with J&J as the world’s largest healthcare company prepares to start clinical trials of its candidate next month, European diplomats said.
The contacts with J&J, first reported by Reuters, come after the European Commission unveiled a plan to spend billions of euros on advanced purchase deals with drugs businesses to obtain vaccine supplies for EU countries.
The growing efforts by rich nations including the US to strike such agreements has stoked fears that poorer nations will be squeezed out of access.
June 18, 2020

Forbes
http://www.forbes.com/
Accessed 20 June 2020
Jun 19, 2020
Immunity To Covid-19 Infection May Fade Quickly
A new study published in Nature Medicine indicates that immunity to infection by SARS-CoV-2 may fade quickly, at least in people with no or moderate symptoms.
By William A. Haseltine Contributor

Jun 18, 2020
Fauci Says He’ll Oppose Any Rush To Unveil Coronavirus Vaccine In Trump’s ‘Operation Warp Speed’
“There is no chance in the world I’m going to be forced into agreeing to something that I don’t think is safe and scientifically sound.”
By Jemima McEvoy Contributor

Jun 16, 2020
9 Pharmaceutical Companies Racing For A COVID-19 Vaccine
Globally, there are more than 100 vaccines under development — with nine of them in human clinical trials already, asserts equity analyst Sel Hardy, in CFRA Research’s flagship newsletter, The Outlook.
By MoneyShow Contributor

Foreign Affairs
http://www.foreignaffairs.com/
Accessed 20 June 2020
[No new, unique, relevant content]

Foreign Policy
http://foreignpolicy.com/
Accessed 20 June 2020 | [No new, unique, relevant content]
[No new, unique, relevant content]

The Guardian
http://www.guardiannews.com/
[No new, unique, relevant content]

New Yorker
http://www.newyorker.com/
Accessed 20 June 2020
[No new, unique, relevant content]

New York Times
http://www.nytimes.com/
Accessed 20 June 2020
[No new, unique, relevant content]

Washington Post
https://www.washingtonpost.com/
Accessed 20 June 2020
Trump pushing officials to speed up already-ambitious coronavirus vaccine timeline
Yasmeen Abutaleb, Josh Dawsey, Laurie McGinley and Carolyn Y. Johnson
Jun 17, 2020

US expects insurers to cover COVID vaccine without copays
Jun 16, 2020

Germany to take stake in company working on virus vaccine [CureVac]

Jun 15, 2020

Think Tanks et al

Brookings
http://www.brookings.edu/
Accessed 20 June 2020
[No new relevant content]

Center for Global Development [to 20 June 2020]
http://www.cgdev.org/page/press-center
Accessed 20 June 2020
June 16, 2020
What Can Policymakers Learn about COVID-19 from Looking at Different Model Estimates?
Because of the uncertainties that complicate modelling, there is value in different research groups working independently to build models. Different models will employ different methods, data, and assumptions and will seek to answer different policy questions. Here we take a look from an end-user’s perspective at what models can tell us, by looking for one example country, the Republic of South Africa.
Y-Ling Chi, Kalipso Chalkidou and Damian Walker

June 15, 2020
Using Military Health Systems in the Response to COVID-19
COVID-19 has placed an unimaginable strain on health systems across the world, especially in regions that have been hit hardest. Some countries have utilised their armed forces to assist the civilian response to the COVID-19 crisis. Recognising the important relationship between the military and medical institutions this blog outlines how militaries around the world–but specifically in eight European countries–have been feeding into the COVID-19 response.
Joseph Kazibwe et al.

Chatham House [to 20 June 2020]
https://www.chathamhouse.org/
[No new relevant content]

CSIS
https://www.csis.org/
Accessed 20 June 2020
[No new relevant content]

Council on Foreign Relations
http://www.cfr.org/
Accessed 20 June 2020
June 15, 2020
United States
The State of U.S. Strategic Stockpiles
The coronavirus pandemic has renewed attention on the Strategic National Stockpile, the nation’s emergency reserve of medical supplies. It’s just one of the stockpiles the United States maintains for…
Backgrounder by Anshu Siripurapu

Kaiser Family Foundation
https://www.kff.org/search/?post_type=press-release
Accessed 20 June 2020
[No new relevant content]

EMERGENCIES

Coronavirus [COVID-19]
Public Health Emergency of International Concern (PHEIC)

WHO – Situation report – 145
Coronavirus disease 2019 (COVID-19)  13 June 2020
Confirmed cases :: 7 553 182
Confirmed deaths :: 423 349
Countries, areas or territories with cases :: 216

Highlights
As of 13 June 10am (CEST), Chinese authorities reported to WHO 12 new confirmed cases, among them 6 in Beijing. After 10am (CEST), Chinese authorities reported additional information about an ongoing investigation of further cases in Beijing. Information about the investigation in Beijing will be made available separately and additional cases reported in subsequent Situation Reports.

:: WHO COVID-19 Webpage: https://www.who.int/emergencies/diseases/novel-coronavirus-2019
:: Daily WHO situation reports here: https://www.who.int/emergencies/diseases/novel-coronavirus-2019/situation-reports
:: WHO Coronavirus disease (COVID-2019) daily press briefings here: https://www.who.int/emergencies/diseases/novel-coronavirus-2019/media-resources/press-briefings

WHO Director-General’s opening remarks at the media briefing on COVID-19 – 12 June 2020
12 June 2020
…As the pandemic accelerates in low- and middle-income countries, WHO is especially concerned about its impact on people who already struggle to access health services – often women, children and adolescents.
The indirect effects of COVID-19 on these groups may be greater than the number of deaths due to the virus itself.
Because the pandemic has overwhelmed health systems in many places, women may have a heightened risk of dying from complications of pregnancy and childbirth.
WHO has developed guidance for health facilities and community activities on maintaining essential services, including for women, newborns, children and adolescents.
This includes ensuring women and children can use services with appropriate infection prevention and control measures, and respectful maternal and newborn care.
WHO has also carefully investigated the risks of women transmitting COVID-19 to their babies during breastfeeding.
We know that children are at relatively low-risk of COVID-19, but are at high risk of numerous other diseases and conditions that breastfeeding prevents.
Based on the available evidence, WHO’s advice is that the benefits of breastfeeding outweigh any potential risks of transmission of COVID-19…

::::::
::::::

Emergencies

Ebola – DRC+
Public Health Emergency of International Concern (PHEIC)

No link between two ongoing Ebola outbreaks in the Democratic Republic of the Congo – WHO
09 June 2020
Kinshasa/Brazzaville – New genetic sequence analysis by the Democratic Republic of the Congo’s (DRC) National Institute of Biomedical Research (INRB) has found that the newly-identified Ebola virus circulating in the Equateur Province in western DRC is different from the one which has infected more than 3400 people in the eastern part of the country.

The DRC’s 11th Ebola outbreak was announced on 1 June 2020 after a cluster of cases was detected in the Mbandaka area of Equateur Province. The INRB genetic sequencing analysis also found that the virus in the latest outbreak is distinct from the previous one that hit the same region in 2018. The investigation is ongoing to determine the source of the new outbreak, but it is likely that it originated from an animal source.

“We are not surprised to find no link between the current outbreak in Mbandaka and the two previous ones. The ongoing Ebola outbreaks are far apart and there is a flight ban in place due to COVID-19,” said Dr Matshidiso Moeti, World Health Organization (WHO) Regional Director for Africa. “National health authorities supported by WHO and partners have led an effective response against Ebola in eastern DRC despite huge challenges. We expect the same national expertise will be leveraged to overcome the current outbreak in Mbandaka.”

WHO has more than 20 staff on the ground supporting the Ministry of Health and partners responding to the outbreak in Mbandaka and the rural community of Bikoro. Additional staff will arrive this week to support the Ministry of Health in containing the outbreak. WHO has worked with the DRC Ministry of Health, Africa Centres for Disease Control and Prevention, the Red Cross Movement, UNICEF and other partners over the past two years to strengthen capacity to respond to Ebola outbreaks in the DRC.

“Ebola is endemic in animal reservoirs in the DRC, so it was expected that new cases would emerge,” said Dr Moeti. “While the new Ebola outbreak in Mbandaka represents a challenge, it’s one we are ready to tackle. With each experience we respond faster and more effectively.”
Together with the Ministry of Health and partners, WHO has deployed vaccinators to the affected areas. More than 600 people have been vaccinated in Mbandaka and Wangata health zones…

Ebola Outbreak in DRC 96: 10 June 2020
[Excerpts]
Situation Update WHO Health Emergencies Programme Page 2
The Ebola virus disease (EVD) outbreak in Equateur Province, Democratic Republic of the Congo, continues since its declaration on 1 June 2020 by the Ministry of Health. Since our last situation report on 2 June 2020 (External Situation report 95), four additional confirmed EVD cases and four deaths have been reported. As of 8 June 2020, a total of 12 EVD cases (9 confirmed and 3 probable), including eight deaths (case fatality ratio 66.7%), have been reported from six health areas in three health zones. Of the eight deaths, four occurred in the community. The case fatality ratio among confirmed cases is 55.6% (5 deaths/9 confirmed cases). Two health workers are among the confirmed cases since the start of the outbreak, 18.2% of all cases. Of the four confirmed cases still alive, two are under treatment in the Ebola treatment centre and two are in the community…

Conclusions
The new outbreak of EVD in Equateur Province comes in the context of a country already burdened with a long-standing EVD outbreak in North Kivu and Ituri, the COVID-19 outbreak (affecting mainly Kinshasa), an ongoing measles outbreak and a complex humanitarian crisis.

Mbandaka is a large town with a population of 1.2 million people with air and river links to Kinshasa and Boende, increasing the risk of localised spread. The risk of disruption to surveillance and routine public health activities as a result of the COVID-19 response will potentially harm the country’s ability to rapidly contain the re-emergence of EVD. Public health measures, particularly a strong and robust surveillance system, required to detect, isolate and treat new suspected cases as early as possible is required to break any new chains of transmission, along with full community engagement with response measures.

Investigations into the origin of the last cluster of cases in Beni Health Zone are ongoing. Maintaining a robust surveillance system in order to detect, isolate, test and treat new suspected cases as early as possible remains crucial. Continued coordination, communication among partners, authorities and affected communities along with EVD survivor advocacy remain essential in this response.

::::::
::::::

Emergencies

POLIO
Public Health Emergency of International Concern (PHEIC)

Polio this week as of 09 June 2020
Summary of new viruses this week (AFP cases and ES positives):
:: Pakistan: one WPV1 case and 20 positive environmental samples
:: Côte d’Ivoire: five cVDPV2 positive environmental samples

GPEI welcomes the strong commitment of partners at Global Vaccine Summit
US$ 8.8 billion pledged to fund immunization through Gavi, the Vaccine Alliance.
09/06/2020
On 4 June 2020, the UK Government hosted Gavi’s third donor pledging conference, the Global Vaccine Summit, to mobilize at least US$ 7.4 billion to protect the next generation with vaccines, reduce disease inequality and create a healthier, safer and more prosperous world. Responding to this unique call for global solidarity, leaders from donor countries and the private sector made unprecedented commitments of US$ 8.8 billion in order to save up to 8 million lives.
Since 2019, the Global Polio Eradication Initiative (GPEI) has strengthened its collaboration with Gavi, inviting Gavi to become the sixth core partner of the GPEI. While the GPEI will continue its focus on interrupting virus transmission and eradicating polio through immunization campaigns using the oral polio vaccine (OPV), Gavi’s support for the inactivated polio vaccine (IPV) at an estimated cost of US$ 800 million during its 2021-25 strategic period represents the insurance policy for the success of the Polio Endgame Strategy…

::::::
::::::

WHO Grade 3 Emergencies [to 13 June 2020]

Democratic Republic of the Congo
:: No link between two ongoing Ebola outbreaks in the Democratic Republic of the Congo 9 June 2020
:: Ebola Outbreak in DRC 96: 10 June 2020
[See Ebola above for detail]

Nigeria – No new digest announcements identified
Somalia – No new digest announcements identified
South Sudan – No new digest announcements identified
Syrian Arab Republic – No new digest announcements identified
Yemen – No new digest announcements identified

::::::

WHO Grade 2 Emergencies [to 13 June 2020]
Burkina Faso [in French]
:: Riposte au COVID-19 : l’OMS renforce les capacités et la biosécurité des laboratoire…
12 juin 2020
Sudan
:: Training health workers to fight COVID-19 in Sudan 28 May 2020

Angola – No new digest announcements identified
Afghanistan – No new digest announcements identified
Burundi – No new digest announcements identified
Cameroon – No new digest announcements identified
Central African Republic – No new digest announcements identified
Ethiopia – No new digest announcements identified
Iraq – No new digest announcements identified
Libya – No new digest announcements identified
Malawi – No new digest announcements identified
Measles in Europe – No new digest announcements identified
MERS-CoV – No new digest announcements identified
Myanmar – No new digest announcements identified
Niger – No new digest announcements identified
occupied Palestinian territory – No new digest announcements identified
Ukraine – No new digest announcements identified
Zimbabwe – No new digest announcements identified

::::::

WHO Grade 1 Emergencies [to 13 June 2020]

Chad – No new digest announcements identified
Djibouti – Page not responding at inquiry
Kenya – No new digest announcements identified
Mali – No new digest announcements identified
Namibia – viral hepatitis – No new digest announcements identified
Tanzania – No new digest announcements identified

::::::
::::::

UN OCHA – L3 Emergencies
The UN and its humanitarian partners are currently responding to three ‘L3’ emergencies. This is the global humanitarian system’s classification for the response to the most severe, large-scale humanitarian crises. 
Syrian Arab Republic
:: Recent Developments in Northwest Syria – Situation Report No. 15 – As of 12 June 2020
HIGHLIGHTS
:: The Syrian Pound has halved in value since the beginning of May, pushing prices of basic necessities to record highs and further out of reach for people in northwest Syria.
:: Renewed displacement has been reported from some parts of southern Idleb governorate and northern Hama governorate following hostilities in the area.
:: No laboratory confirmed COVID-19 cases identified in northwest Syria to date. Efforts remain focused on awareness raising and measures to mitigate an outbreak, with preparation for an effective response in the event of any cases.
:: Major humanitarian needs persist across all sectors. Due to the pressures of COVID-19 mitigation measures and the economic deterioration, there are increasing reports of gender-based protection issues such as short-term marriages, domestic violence, divorces and forced abortions.

Yemen – No new digest announcements identified

::::::

UN OCHA – Corporate Emergencies
When the USG/ERC declares a Corporate Emergency Response, all OCHA offices, branches and sections provide their full support to response activities both at HQ and in the field.
CYCLONE IDAI and Kenneth
::  11 June 2020 Zimbabwe Situation Report, 11 Jun 2020

EBOLA OUTBREAK IN THE DRC – No new digest announcements identified

::::::
::::::

WHO & Regional Offices [to 13 June 2020]

Weekly Epidemiological Record, 5 June 2020, vol. 95, 23/24 (pp. 257–264)
Fast-tracking WHO’s COVID-19 technical guidance to training for the frontline

::::::

WHO Regional Offices
Selected Press Releases, Announcements
WHO African Region AFRO
:: Africa records over 200 000 COVID-19 cases 11 June 2020
COVID-19 continues to spread in Africa since the virus was first detected on the continent in mid-February 2020. More than 200 000 cases have been confirmed so far, with over 5600 deaths. The pandemic is accelerating – it took 98 days to reach 100 000 cases and only 19 days to move to 200 000 cases.
:: No link between two ongoing Ebola outbreaks in the Democratic Republic of the Congo 09 June 2020

WHO Region of the Americas PAHO
No new digest content identified.

WHO South-East Asia Region SEARO
:: India elected chair of WHO’s Executive Board 22 May 2020

WHO European Region EURO
:: WHO/Europe encourages health workers to ask “why?” 09-06-2020
:: COVID-19: WHO coordinates large-scale response operation in Tajikistan 09-06-2020

WHO Eastern Mediterranean Region EMRO
Website not responding at inquiry

WHO Western Pacific Region
No new digest content identified.

CDC/ACIP [to 13 June 2020]
http://www.cdc.gov/media/index.html
https://www.cdc.gov/vaccines/acip/index.html
Latest News Releases
Transcript – CDC Media Telebriefing: Update on COVID-19
Friday, June 12, 2020
… Thank you all for joining us today for this briefing to update you on the CDC’s COVID-19-19 response.  We are joined by director Dr. Robert Redfield and CDC’s incident manager Dr. Jay Butler.  Dr. Redfield will give opening remarks and Dr. Butler will discuss an MMWR being released later today as well as suggestions on how to navigate daily life as communities reopen.

MMWR News Synopsis Friday, June 12, 2020
Trends in Pneumoconiosis Deaths — United States, 1999–2018

Impact of the COVID-19 Pandemic on Emergency Department Visits — United States, January 1, 2019–May 30, 2020 (Early release June 3, 2020)

Knowledge and Practices Regarding Safe Household Cleaning and Disinfection for COVID-19 Prevention — United States, May 2020 (Early release June 5, 2020)

First Reported Cases of SARS-CoV-2 Infection in Companion Animals — New York, March–April 2020 (Early release June 8, 2020)

SARS-CoV-2 Infections and Serologic Responses from a Sample of U.S. Navy Service Members — USS Theodore Roosevelt, April 2020 (Early release June 9, 2020)

Africa CDC [to 13 June 2020]
http://www.africacdc.org/
News
Outbreak Brief 21: COVID-19 Pandemic – 9 June 2020
…As of 9 am EAT 9 June 2020, a total of 196,254 COVID-19 cases and 5,341 (CFR: 2.7%) deaths have been reported in 54 African countries. This is about 2.8% of all cases reported globally. Since the last brief (2 June 2020), 43,812 new COVID-19 cases have been reported, which is a 29% increase in new cases reported compared to what was reported in the previous week (26 May to 2 June 2020)…

China CDC
http://www.chinacdc.cn/en/
No new digest content identified.

National Health Commission of the People’s Republic of China
http://en.nhc.gov.cn/
News
June 13: Daily briefing on novel coronavirus cases in China
On June 12, 31 provincial-level regions on the Chinese mainland as well as the Xinjiang Production and Construction Corps reported 11 new cases of confirmed infections, no new cases of suspected infections, and no deaths

Xi hails strengthened ties in pandemic fight
2020-06-12

Beijing CDC: proper use of face masks still necessary
2020-06-12

Beijing reports new case after more than 50 days
2020-06-12

China donates more medical supplies to Lebanon to fight COVID-19
2020-06-12

Announcements

Paul G. Allen Frontiers Group [to 13 June 2020]
https://alleninstitute.org/what-we-do/frontiers-group/news-press/
News
No new digest content identified.

BARDA [to 13 June 2020]
https://www.phe.gov/about/barda/Pages/default.aspx
June 11, 2020:
BARDA, Snapdragon Chemistry Inc., demonstrate deployable domestic manufacturing technology for COVID-19 vaccine component

BMGF – Gates Foundation [to 13 June 2020]
http://www.gatesfoundation.org/Media-Center/Press-Releases
JUNE 11, 2020
Bill & Melinda Gates Foundation Appoints President of Gender Equality
SEATTLE, June 11, 2020 – Today the Bill & Melinda Gates Foundation named Anita Zaidi, currently director, Vaccine Development & Surveillance (VD&S) and Enteric & Diarrheal Diseases (EDD), as the first president of Gender Equality. In this new role, Anita will oversee a division comprised of the foundation’s Gender Equality program team and Gender Program Advocacy and Communications team. She will also take on responsibility for the foundation’s broader gender integration agenda, working with and across all program teams to ensure gender is being incorporated in a smart, thoughtful way to increase impact. Anita will report directly to CEO Mark Suzman and will join the Executive Leadership Team (ELT). She will assume her new role effective November 2, 2020.

JUNE 10, 2020
Changing the National Conversation About Poverty and Economic Mobility
28 organizations from 18 states and D.C. receive $100,000 Grand Challenge Grants, Sponsored by a Group of 8 Philanthropic Partners

Bill & Melinda Gates Medical Research Institute [to 13 June 2020]
https://www.gatesmri.org/
The Bill & Melinda Gates Medical Research Institute is a non-profit biotech organization. Our mission is to develop products to fight malaria, tuberculosis, and diarrheal diseases—three major causes of mortality, poverty, and inequality in developing countries. The world has unprecedented scientific tools at its disposal; now is the time to use them to save the lives of the world’s poorest people
No new digest content identified.

CARB-X [to 13 June 2020]
https://carb-x.org/
CARB-X is a non-profit public-private partnership dedicated to accelerating antibacterial research to tackle the global rising threat of drug-resistant bacteria.
No new digest content identified.

CEPI – Coalition for Epidemic Preparedness Innovations [to 13 June 2020]
http://cepi.net/
Latest News
Greece announces $1.6 million funding to CEPI to support COVID-19 vaccine development
The donation, first announced by Prime Minister of Greece Kyriakos Mitsotakis on 4 May, will contribute to CEPI’s efforts to advance the development of a safe, effective and globally accessible…
COVID-19
09 Jun 2020

Clinton Health Access Initiative, Inc. (CHAI) [to 13 June 2020]
https://clintonhealthaccess.org/
News & Press Releases
No new digest content identified.

EDCTP [to 13 June 2020]
http://www.edctp.org/
The European & Developing Countries Clinical Trials Partnership (EDCTP) aims to accelerate the development of new or improved drugs, vaccines, microbicides and diagnostics against HIV/AIDS, tuberculosis and malaria as well as other poverty-related and neglected infectious diseases in sub-Saharan Africa, with a focus on phase II and III clinical trials
Latest news
09 June 2020
WHO AVAREF survey highlights EDCTP’s role in supporting ethical and regulatory oversight in Africa
In April 2020, the African Vaccine Regulatory Forum (AVAREF) conducted a digital survey of the state of regulatory activities and ethical review in Africa. On 21 May 2020, the results were presented at a webinar organised by WHO AFRO through the AVAREF Secretariat, which was attended by approximately 125 partners of AVAREF including EDCTP. The survey focused on AVAREF’s joint review process. The results highlight EDCTP’s role in strengthening the capacity for ethics review in African countries, including the use of online platforms…

Emory Vaccine Center [to 13 June 2020]
http://www.vaccines.emory.edu/
No new digest content identified.

European Medicines Agency [to 13 June 2020]
http://www.ema.europa.eu/ema/
News & Press Releases
Press release: Highlights of Management Board: June 2020 meeting
MB, Last updated: 12/06/2020

News: Meeting highlights from the Pharmacovigilance Risk Assessment Committee (PRAC) 8-11 June 2020
PRAC, Last updated: 12/06/2020

Press release: Latest data support continued use of ACE inhibitors and ARB medicines during COVID-19 pandemic
Last updated: 09/06/2020

Press release: EU actions to support availability of medicines during COVID-19 pandemic – update #7
Last updated: 08/06/2020
Press release: EMA receives application for conditional authorisation of first COVID-19 treatment in the EU
Last updated: 08/06/2020

News: Patients’ and healthcare professionals’ organisations updated on EMA’s response to COVID-19
Last updated: 04/06/2020

European Vaccine Initiative [to 13 June 2020]
http://www.euvaccine.eu/
Latest News
Website not responding at inquiry

FDA [to 13 June 2020]
https://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/default.htm
Press Announcements
June 12, 2020 – Coronavirus (COVID-19) Update: Daily Roundup June 12, 2020

June 12, 2020 – FDA Approves Drug to Treat Infants and Children with HIV

June 11, 2020 – Coronavirus (COVID-19) Update: Daily Roundup June 11, 2020

June 10, 2020 – Coronavirus (COVID-19) Update: Daily Roundup June 10, 2020

June 10, 2020 – Coronavirus (COVID-19) Update: FDA Authorizes First Next Generation Sequence Test for Diagnosing COVID-19

June 9, 2020 – Coronavirus (COVID-19) Update: Daily Roundup June 9, 2020

June 8, 2020 – Coronavirus (COVID-19) Update: Daily Roundup June 8, 2020

June 7, 2020 – Coronavirus (COVID-19) Update: FDA Reissues Emergency Use Authorizations Revising Which Types of Respirators Can Be Decontaminated for Reuse

Fondation Merieux [to 13 June 2020]
http://www.fondation-merieux.org/
News, Events
No new digest content identified.

Gavi [to 13 June 2020]
https://www.gavi.org/
News releases
No new digest content identified.

GHIT Fund [to 13 June 2020]
https://www.ghitfund.org/newsroom/press
GHIT was set up in 2012 with the aim of developing new tools to tackle infectious diseases that No new digest content identified.

Global Fund [to 13 June 2020]
https://www.theglobalfund.org/en/news/
Voices
In Kenya, A Chance to See Communities Confront COVID-19
09 June 2020

Updates
43rd Board Meeting Documents
09 June 2020

Hilleman Laboratories [to 13 June 2020]
http://www.hillemanlabs.org/
No new digest content identified.

Human Vaccines Project [to 13 June 2020]
http://www.humanvaccinesproject.org/media/press-releases/
No new digest content identified.

IAVI [to 13 June 2020]
https://www.iavi.org/newsroom
Press Releases
No new digest content identified.

International Coalition of Medicines Regulatory Authorities [ICMRA]
http://www.icmra.info/drupal/en/news
Selected Statements, Press Releases, Research
No new digest content identified.

International Generic and Biosimilar Medicines Association [IGBA]
https://www.igbamedicines.org/
News
No new digest content identified.

IFFIm
http://www.iffim.org/
Press Releases
Norway contributes NOK 2 billion to IFFIm
The pledge will back Vaccine Bonds, funding CEPI’s COVID-19 programme
London, 12 June 2020 – The Kingdom of Norway has committed NOK 2 billion (approximately US$ 200 million) to the International Finance Facility for Immunisation (IFFIm) to issue Vaccine Bonds that will expedite funding through Gavi…

IFRC [to 13 June 2020]
http://media.ifrc.org/ifrc/news/press-releases/
Selected Press Releases, Announcements
No new digest content identified.

IVAC [to 13 June 2020]
https://www.jhsph.edu/research/centers-and-institutes/ivac/index.html
Updates
Webinar: How will a COVID-19 Vaccine be Delivered?
June 2020
Register: The International Vaccine Access Center (IVAC) on June 17, 2020 at 1pm ET will host a 60-minute webinar, “How will a COVID-19 Vaccine be Delivered?“. Description: When a COVID-19 vaccine becomes available, it will effectively stop disease transmission only if it reaches the people who need it. Many decisions go into developing a strategy […]

IVI [to 13 June 2020]
http://www.ivi.int/
Selected IVI News & Announcements
No new digest content identified.

JEE Alliance [to 13 June 2020]
https://www.jeealliance.org/
Selected News and Events
No new digest content identified.

MSF/Médecins Sans Frontières [to 13 June 2020]
http://www.msf.org/
Latest [Selected Announcements]
Coronavirus COVID-19 pandemic
Caring for COVID-19 patients in Tegucigalpa
Project Update 13 Jun 2020

El Salvador
Tropical Storm Amanda is “the last straw” for families in El Salvador amid COVI…
Project Update 11 Jun 2020

Coronavirus COVID-19 pandemic
“COVID-19 has brought suffering to people everywhere, but its impact…
Speech 10 Jun 2020

Afghanistan
“As midwives in Afghanistan, we are the silent leaders of our count…
Voices from the Field 10 Jun 2020

Coronavirus COVID-19 pandemic
“COVID-19 has made the health system’s collapse complete” in Yemen
Project Update 10 Jun 2020

DRC Ebola outbreaks
Crisis update – June 2020
Crisis Update 9 Jun 2020

National Vaccine Program Office – U.S. HHS [to 13 June 2020]
https://www.hhs.gov/vaccines/about/index.html
NVAC 2020 Meetings
September 23-24, 2020 Meeting (Virtual)

NIH [to 13 June 2020]
http://www.nih.gov/news-events/news-releases
Selected News Releases
Brain cells can harbor and spread HIV virus to the body
June 11, 2020 — NIH-funded study highlights the importance of addressing the brain in HIV cure strategies.

NIH researchers identify key genomic features that could differentiate SARS-CoV-2 from other coronaviruses that cause less severe disease
June 11, 2020 — Research could be a crucial step in helping scientists develop approaches to predict severity of future coronavirus disease outbreaks.

NIH-funded study to evaluate drugs prescribed to children with COVID-19
June 10, 2020 — Researchers will assess dosage, metabolism and other properties not yet determined in children.

PATH [to 13 June 2020]
https://www.path.org/media-center/
Selected Announcements
Racism is a centuries-long public health crisis that demands a public health response.
June 2, 2020 by PATH

Sabin Vaccine Institute [to 13 June 2020]
http://www.sabin.org/updates/pressreleases
Statements and Press Releases
Our Commitment to Anti-Racism
Saturday, June 6, 2020
In our strongest and most unified voice, the Sabin Vaccine Institute condemns racism. Dr. Albert Sabin was a great scientist, and importantly his work led him to fight for equality so that all children everywhere – regardless of race, religion, nationality, gender or socioeconomic status – received his lifesaving polio vaccine.

UNAIDS [to 13 June 2020]
http://www.unaids.org/en
Selected Press Releases/Reports/Statements
12 June 2020
New HIV community group in Guinea fighting COVID-19

11 June 2020
Five UNAIDS country directors taking the lead in the COVID-19 response

10 June 2020
Peer consultants helping the AIDS response in Kyrgyzstan

8 June 2020
New HIV infections differ by sex and by region

8 June 2020
Targeting sex workers is not the answer

UNICEF [to 13 June 2020]
https://www.unicef.org/media/press-releases
Selected Press releases/Announcements
Press release
Geneva Palais briefing note on the humanitarian situation for children in Yemen
This is a summary of what was said by Marixie Mercado, UNICEF spokesperson in Geneva – to whom quoted text may be attributed – at today’s press briefing at the Palais des Nations in Geneva.
12/06/2020

Press release
COVID-19 may push millions more children into child labour – ILO and UNICEF
Child labour down by 94 million since 2000, a gain now under threat
11/06/2020

Press release
Millie Bobby Brown and Sofia Carson join United Nations Deputy Secretary-General Amina Mohammed and UNICEF Executive Director Henrietta Fore in World’s Largest Lesson Live, encouraging teens to reimagine the world post-COVID
10/06/2020

Press release
New UNICEF, NBIM guidance to help businesses prioritize child rights in global supply chains
As the economic fallout of the COVID-19 pandemic threatens livelihoods across the globe, newly released guidance supports companies to improve their impact on children in the garment and footwear supply chain
09/06/2020

Unitaid [to 13 June 2020]
https://unitaid.org/
Featured News
No new digest content identified.

Vaccination Acceptance Research Network (VARN) [to 13 June 2020]
https://vaccineacceptance.org/news.html#header1-2r
Announcements
No new digest content identified.

Vaccine Confidence Project [to 13 June 2020]
http://www.vaccineconfidence.org/
Latest News & Archive
The misinformation circulating in Africa about Covid-19
10 Jun 2020

Vaccine Education Center – Children’s Hospital of Philadelphia [to 13 June 2020]
http://www.chop.edu/centers-programs/vaccine-education-center
No new digest content identified.

Wellcome Trust [to 13 June 2020]
https://wellcome.ac.uk/news
No new digest content identified.

The Wistar Institute [to 13 June 2020]
https://www.wistar.org/news/press-releases
No new digest content identified.

WFPHA: World Federation of Public Health Associations [to 13 June 2020]
https://www.wfpha.org/
Latest News
WFPHA Press Release: 54th General Assembly
Thursday, 11 June 2020
This year, General Assembly was very special: first time ever online and everyone behind a screen. This has never happened in the history of our…

World Organisation for Animal Health (OIE) [to 13 June 2020]
https://www.oie.int/en/for-the-media/press-releases/2020/
Press Releases
12/06/20
The OIE Working Group on Antimicrobial Resistance:Providing guidance and establishing priorities during its first year
Paris, 12 June 2020 – The Working Group on AMR is focused on assisting in the implementation of the OIE Strategy on AMR and the Prudent and Responsible Use of Antimicrobials, providing guidance, establishing priorities, addressing recommendations to maintain and develop the OIE International Standards related to AMR, assisting in the development of the OIE Antimicrobial Use database and supporting OIE Member Countries in developing communication activities and National Action Plans relating to AMR. The Working Group on AMR will also support the implementation of the recommendations of the 2nd OIE Global Conference on AMR and Prudent Use of Antimicrobials in Animals…

::::::

ARM [Alliance for Regenerative Medicine] [to 13 June 2020]
https://alliancerm.org/press-releases/
Press Releases
ARM Statement on Racial Inequality & Injustice
June 5, 2020

BIO [to 13 June 2020]
https://www.bio.org/press-releases
Press Releases
New Report Analyzes Bioscience Industry’s Impact on Economy & Global Pandemic
June 8, 2020
The Biotechnology Innovation Organization (BIO) today released new data on the bioscience industry in the United States. The new report, The Bioscience Economy: Propelling Life-Saving Treatments, Supporting State & Local Communities,…

DCVMN – Developing Country Vaccine Manufacturers Network [to 13 June 2020]
http://www.dcvmn.org/
News
DCVMN members’ commitments on Cholera, Typhoid and HPV vaccines supply for Gavi eligible countries
04th June 2020

IFPMA [to 13 June 2020]
http://www.ifpma.org/resources/news-releases/
Selected Press Releases, Statements, Publications
Global Pharma Body Names New Communications Director
08 June 2020

ICBA – International Council of Biotechnology Associations [to 13 June 2020]
https://internationalbiotech.org/
News
No new digest content identified.

PhRMA [to 13 June 2020]
http://www.phrma.org/
Selected Press Releases, Statements
Stakeholders raise concerns with proposed drastic changes to the pharmaceutical supply chain
Nicole Longo   |     June 11, 2020
As we work to combat the current global pandemic, it is especially critical to maintain the stability of our global manufacturing supply chain. Unfortunately, recent policy proposals that would mandate drastic changes to pharmaceutical manufacturing supply chains underestimate the significant time, resources and other feasibility challenges and complexities involved. Proponents of these proposals also ignore the strength of a geographically diverse global supply chain…

Industry Watch [to 13 June 2020]
:: FDA Approves Merck’s GARDASIL 9 for the Prevention of Certain HPV-Related Head and Neck Cancers
June 12, 2020

:: Moderna Advances Late-Stage Development of its Vaccine (mRNA-1273) Against COVID-19
June 11, 2020

:: Johnson & Johnson Announces Acceleration of its COVID-19 Vaccine Candidate; Phase 1/2a Clinical Trial to Begin in Second Half of July
Jun 10, 2020, 10:00 ET

Journal Watch
Vaccines and Global Health: The Week in Review continues its weekly scanning of key peer-reviewed journals to identify and cite articles, commentary and editorials, books reviews and other content supporting our focu-s on vaccine ethics and policy. Journal Watch is not intended to be exhaustive, but indicative of themes and issues the Center is actively tracking. We selectively provide full text of some editorial and comment articles that are specifically relevant to our work. Successful access to some of the links provided may require subscription or other access arrangement unique to the publisher.
If you would like to suggest other journal titles to include in this service, please contact David Curry at: david.r.curry@centerforvaccineethicsandpolicy.org

American Journal of Tropical Medicine and Hygiene
Volume 102, Issue 6, June 2020
http://www.ajtmh.org/content/journals/14761645/102/6

oa Ivermectin and COVID-19: Keeping Rigor in Times of Urgency
Carlos Chaccour, Felix Hammann, Santiago Ramón-García and N. Regina Rabinovich
Pages: 1156–1157
https://doi.org/10.4269/ajtmh.20-0271
… The discovery of ivermectin’s activity against SARS-CoV-2 gives reason for hope, but off-label and compassionate use requires careful risk–benefit considerations,²⁷ especially in critically ill patients. A path to consider is evaluation first of impacts on virologic outcomes in uncomplicated, low-risk patients early in the course of the disease. Well-conducted clinical trials informed by robust pharmacokinetic models should be considered to validate the impact before the use of ivermectin to treat SARS-CoV-2 is implemented.

American Journal of Tropical Medicine and Hygiene
Volume 102, Issue 6, June 2020
http://www.ajtmh.org/content/journals/14761645/102/6

oa Rigorous Randomized Controlled Trial Implementation in the Era of COVID-19
Catherine E. Oldenburg and Thuy Doan
Pages: 1154–1155
https://doi.org/10.4269/ajtmh.20-0262