Effective study design for comparative functional genomics

Nature Reviews Genetics
Volume 21 Issue 7, July 2020
https://www.nature.com/nrg/volumes/21/issues/7

 

Comment | 24 April 2020
Effective study design for comparative functional genomics
Comparative studies struggle to balance technical properties with the need to obtain samples from multiple species. The authors argue for extensive record keeping and reporting of metadata to minimize the effect of confounders and increase the robustness of inferences from these studies.
Joanna L. Kelley  & Yoav Gilad