Nature Reviews Drug Discovery
Volume 19 Issue 7, July 2020
Review Article | 06 April 2020
Next-generation stem cells — ushering in a new era of cell-based therapies
Primary stem cells have long been used therapeutically for applications such as bone marrow transplantation. This Review discusses how cell-engineering approaches are enabling the development of next-generation stem cell therapies with improved function, specificity and responsiveness, thereby expanding their applications into areas such as delivering drugs and oncolytic viruses to tumours and promoting tissue repair in various diseases.
Erin A. Kimbrel & Robert Lanza