Volume 38 Issue 7, July 2020
Focus on CRISPR tools and therapies
Review Article | 29 June 2020
The delivery challenge: fulfilling the promise of therapeutic genome editing
As CRISPR therapies move into clinical testing, David Schaffer and colleagues review a raft of different delivery technologies being road tested to address cargo capacity limitations, maximize potency, minimize off-target effects and avoid immunogenicity.
Joost van Haasteren, Jie Li[…] & David V. Schaffer