Electronic health records and polygenic risk scores for predicting disease risk

Nature Reviews Genetics
Volume 21 Issue 8, August 2020
https://www.nature.com/nrg/volumes/21/issues/8

 

Review Article | 31 March 2020
Electronic health records and polygenic risk scores for predicting disease risk
Electronic health records (EHRs) linked to biobanks provide new opportunities for developing and applying polygenic risk scores in the clinic. The authors review the opportunities and challenges that arise when using EHR data for the systematic evaluation of patient disease susceptibilities.
Ruowang Li, Yong Chen[…] & Jason H. Moore