Compassionate drug (mis)use during pandemics: lessons for COVID-19 from 2009

BMC Medicine
http://www.biomedcentral.com/bmcmed/content
(Accessed 22 Aug 2020)

 

Compassionate drug (mis)use during pandemics: lessons for COVID-19 from 2009
Patients were frequently treated for pandemic influenza with drugs not registered for this indication, but rarely under circumstances of high-quality data capture. The result was a reliance on use under compassionate circumstances, resulting in continued uncertainty regarding the potential benefits and harms of anti-viral treatment. Rapid scaling of clinical trials is critical for generating a quality evidence base during pandemics.
Authors: Amanda M. Rojek, Genevieve E. Martin and Peter W. Horby
Citation: BMC Medicine 2020 18:265
Content type: Research article
Published on: 21 August 2020