New England Journal of Medicine
August 27, 2020 Vol. 383 No. 9
Covid-19 and Immunity in Aging Populations — A New Research Agenda
Wayne C. Koff, Ph.D.,
and Michelle A. Williams, Sc.D.
The race is on throughout the world to develop Covid-19 vaccines and therapeutics and end a pandemic that threatens to infect a substantial portion of the planet’s population and perhaps kill millions of people, especially older adults. As billions of dollars flow into research and development efforts aimed at controlling the virus, the pandemic response remains hamstrung by our limited understanding of how to generate effective immunity, particularly in the elderly…