An Overview of the Development of New Vaccines for Tuberculosis

Vaccines — Open Access Journal
http://www.mdpi.com/journal/vaccines
(Accessed 10 Oct 2020)

 

Open Access Review
An Overview of the Development of New Vaccines for Tuberculosis
by E. Whitlow, A. S. Mustafa and S. N. M. Hanif
Vaccines 2020, 8(4), 586; https://doi.org/10.3390/vaccines8040586 – 05 Oct 2020
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Abstract
Currently, there is only one licensed vaccine against tuberculosis (TB), the Bacillus Calmette–Guérin (BCG). Despite its protective efficacy against TB in children, BCG has failed to protect adults against pulmonary TB, lacks therapeutic value, and causes complications in immunocompromised individuals. Furthermore, it compromises