SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness

Nature
Volume 586 Issue 7830, 22 October 2020
http://www.nature.com/nature/current_issue.html

 

Article | 05 August 2020
SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness
mRNA-1273, an mRNA vaccine that encodes a stabilized prefusion-state severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein, elicits robust immune responses and protects mice against replication of SARS-CoV-2 in the upper and lower airways.
Kizzmekia S. Corbett, Darin K. Edwards[…] & Barney S. Graham