Volume 586 Issue 7830, 22 October 2020
The cover image draws on aspects of Bauhaus artist Paul Klee’s famous notebooks to reimagine the quest for a vaccine against SARS-CoV-2. The drive to create an effective vaccine to mitigate the COVID-19 pandemic has seen researchers move from genetic sequence of the virus to clinical trials at unprecedented speed. This week’s issue features a number of papers that probe design strategies and clinical trial results for vaccine candidates to combat the virus. In addition, a Review presents a round-up of vaccines in development, noting that signs so far suggest that a safe and effective vaccine could be realized on a timescale of months rather than years.