The carnage of substandard research during the COVID-19 pandemic: a call for quality :: Why continuing uncertainties are no reason to postpone challenge trials for coronavirus vaccines :: Uncertainty, error and informed consent to challenge trials of COVID-19 vaccines: response to Steel et al

Journal of Medical Ethics
December 2020 – Volume 46 – 12
http://jme.bmj.com/content/current

 

Covid 19 Current Controversies
The carnage of substandard research during the COVID-19 pandemic: a call for quality (1 October, 2020) Free
Katrina A Bramstedt
Abstract
Worldwide there are currently over 1200 research studies being performed on the topic of COVID-19. Many of these involve children and adults over age 65 years. There are also numerous studies testing investigational vaccines on healthy volunteers. No research team is exempt from the pressures and speed at which COVID-19 research is occurring. And this can increase the risk of honest error as well as misconduct. To date, 33 papers have been identified as unsuitable for public use and either retracted, withdrawn, or noted with concern. Asia is the source of most of these manuscripts (n=19; 57.6%) with China the largest Asian subgroup (n=11; 57.9%). This paper explores these findings and offers guidance for responsible research practice during pandemics.

Why continuing uncertainties are no reason to postpone challenge trials for coronavirus vaccines (13 July, 2020)
Robert Steel, Lara Buchak, Nir Eyal

Uncertainty, error and informed consent to challenge trials of COVID-19 vaccines: response to Steel et al (8 September, 2020) Free
Arnon Keren, Ori Lev