Antibiotic resistance and persistence—Implications for human health and treatment perspectives

EMBO Reports
Volume 21 Issue 12 3 December 2020
https://www.embopress.org/toc/14693178/current

 

Review 8 December 2020
Antibiotic resistance and persistence—Implications for human health and treatment perspectives
Markus Huemer, Srikanth Mairpady Shambat, Silvio D Brugger, Annelies S Zinkernagel
Bacteria that survive antibiotics challenges are one of the greatest threats to human health. While antibiotic resistance has been well studied, the survival and re‐growth of fully susceptible bacteria, called antibiotic persistence, is less well understood. This review discusses the mechanisms and implications of antibiotic resistance and persistence.