Implication of a High Risk for Type 2 Vaccine-Derived Poliovirus Emergence and Transmission After the Switch From Trivalent to Bivalent Oral Poliovirus Vaccine

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Journal of Infectious Diseases
Volume 223, Issue 1, 1 January 2021
https://academic.oup.com/jid/issue/223/1

 

VIRUSES
Implication of a High Risk for Type 2 Vaccine-Derived Poliovirus Emergence and Transmission After the Switch From Trivalent to Bivalent Oral Poliovirus Vaccine
Dongmei Yan, Dongyan Wang, Yong Zhang, Xiaolei Li, Haishu Tang …
The Journal of Infectious Diseases, Volume 223, Issue 1, 1 January 2021, Pages 113–118, https://doi.org/10.1093/infdis/jiaa386
The switch from trivalent to bivalent oral poliovirus vaccine can provide high-level immunity against type 1 and 3 poliovirus but not against type 2, indicating a high risk of type 2 vaccine-derived poliovirus emergence and transmission.