Implication of a High Risk for Type 2 Vaccine-Derived Poliovirus Emergence and Transmission After the Switch From Trivalent to Bivalent Oral Poliovirus Vaccine

Journal of Infectious Diseases
Volume 223, Issue 1, 1 January 2021
https://academic.oup.com/jid/issue/223/1

 

VIRUSES
Implication of a High Risk for Type 2 Vaccine-Derived Poliovirus Emergence and Transmission After the Switch From Trivalent to Bivalent Oral Poliovirus Vaccine
Dongmei Yan, Dongyan Wang, Yong Zhang, Xiaolei Li, Haishu Tang
The Journal of Infectious Diseases, Volume 223, Issue 1, 1 January 2021, Pages 113–118, https://doi.org/10.1093/infdis/jiaa386
The switch from trivalent to bivalent oral poliovirus vaccine can provide high-level immunity against type 1 and 3 poliovirus but not against type 2, indicating a high risk of type 2 vaccine-derived poliovirus emergence and transmission.